Khater Mohamed H, Khattab Fathia M, Abdelhaleem Manal R
a Departments of Dermatology and Venerology Medicine , Faculty of Medicine, Zagazig University , Zagazig , Egypt.
b Department of Histology , Faculty of Medicine, Zagazig University , Zagazig , Egypt.
J Cosmet Laser Ther. 2016;18(2):75-9. doi: 10.3109/14764172.2015.1063665. Epub 2016 Jan 28.
Striae are atrophic dermal scars with overlying epidermal atrophy causing cosmetic concern. This study assesses and compares the efficacy and safety of needling therapy versus CO2 fractional laser in treatment of striae.
Twenty Egyptian female patients with striae in the abdomen and lower limbs were involved in the study. The patients were treated with needling therapy and CO2 laser every 1 month for 3 sessions. Follow-up by digital photography and skin biopsy was conducted at baseline and 6 months after treatment. Clinical improvement was assessed by comparing photographs and patient's satisfaction before and after treatment.
Nine of 10 (90%) needle-treated patients showed improvement. Among them, 3 (30%) had good, 4 (40%) had fair, and 2 (20%) had poor improvements; however, 1 (10%) did not show any improvement after the treatment. In CO2-laser treated patients, 5 of 10 (50%) of the patients showed clinical improvement; 1 (10%) were good, 3 (30%) were fair, and 1 (10%) were poor; however, 5 (50%) did not show improvement.
The results support the use of microneedle therapy over CO2 lasers for striae treatment.
萎缩纹是伴有表皮萎缩的萎缩性皮肤瘢痕,会引起美观问题。本研究评估并比较针刺疗法与二氧化碳点阵激光治疗萎缩纹的疗效和安全性。
20名患有腹部和下肢萎缩纹的埃及女性患者参与了本研究。患者每1个月接受一次针刺疗法和二氧化碳激光治疗,共治疗3个疗程。在基线期和治疗后6个月通过数码摄影和皮肤活检进行随访。通过比较治疗前后的照片以及患者的满意度来评估临床改善情况。
10名接受针刺治疗的患者中有9名(90%)有改善。其中,3名(30%)改善良好,4名(40%)改善一般,2名(20%)改善较差;然而,1名(10%)患者治疗后未显示任何改善。在接受二氧化碳激光治疗的患者中,10名患者中有5名(50%)显示出临床改善;1名(10%)改善良好,3名(30%)改善一般,1名(10%)改善较差;然而,5名(50%)患者未显示改善。
结果支持使用微针疗法而非二氧化碳激光治疗萎缩纹。