Department of Dermatology, Chung-Ang University College of Medicine, Chung-Ang University Hospital, 224–1 Heukseok-dong, Dongjak-gu, Seoul, Korea.
Dermatol Surg. 2012 Nov;38(11):1823-8. doi: 10.1111/j.1524-4725.2012.02552.x. Epub 2012 Aug 22.
Striae distensae are dermal scars characterized by flattening and atrophy of the epidermis. Although many treatment modalities have been attempted with variable results, there is no criterion standard treatment modality for striae distensae.
To evaluate the effectiveness and safety of a disk microneedle therapy system (DTS) in the treatment of striae distensae.
Sixteen Korean volunteers with striae distensae alba or rubra were enrolled. Patients received three treatments using a DTS at 4-week intervals. Clinical response to treatment was assessed by comparing pre- and post-treatment clinical photographs, skin biopsies, and patient satisfaction scores. Clinical improvement was assessed using the quartile grading scale.
Marked to excellent improvement was noted in seven (43.8%) patients, with minimal to moderate improvement in the remaining nine. Patient satisfaction scores showed that six (37.5%) patients were highly satisfied, eight (50.0%) were somewhat satisfied, and two (12.5%) were unsatisfied. There were no significant side effects except mild pain, erythema, and spotty bleeding.
Disk microneedle therapy system (DTS) can be effectively and safely used in the treatment of striae distensae.
妊娠纹是一种皮肤瘢痕，表现为表皮的扁平及萎缩。尽管已经尝试了多种治疗方法，但尚无妊娠纹的标准治疗方法。
评估磁盘微针治疗系统（DTS）治疗妊娠纹的有效性和安全性。
纳入 16 名患有白色或红色妊娠纹的韩国志愿者。患者每 4 周接受 3 次 DTS 治疗。通过比较治疗前后的临床照片、皮肤活检和患者满意度评分来评估临床疗效。采用四分位等级评分来评估临床改善情况。
7 名（43.8%）患者的改善程度为显著至极好，其余 9 名患者的改善程度为轻度至中度。患者满意度评分显示，6 名（37.5%）患者非常满意，8 名（50.0%）患者满意，2 名（12.5%）患者不满意。除轻度疼痛、红斑和点状出血外，无明显不良反应。
磁盘微针治疗系统（DTS）可有效且安全地用于治疗妊娠纹。
