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一项关于针刺疗法(射频针刺、中胚层针刺和微针疗法)与剥脱性点阵激光(二氧化碳激光、铒钇铝石榴石激光)治疗萎缩性和增生性瘢痕的比较的系统评价。

A systematic review of the comparison between needling (RF-needling, meso-needling, and micro-needling) and ablative fractional lasers (CO, erbium YAG) in the treatment of atrophic and hypertrophic scars.

作者信息

Nobari Niloufar Najar, Tabavar Anahita, Sadeghi Sara, Dehghani Abbas, Kalantari Yasamin, Ghassemi Mohammadreza, Atefi Najmolsadat, Goodarzi Azadeh

机构信息

Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Division of Dermatology, Department of Pediatrics, Alberta Children's Hospital, University of Calgary, Calgary, Alberta, Canada.

出版信息

Lasers Med Sci. 2023 Feb 7;38(1):67. doi: 10.1007/s10103-022-03694-x.

Abstract

The aim of this study is to compare needling (RF-needling, meso-needling, micro-needling) and ablative fractional lasers (CO, erbium-YAG) in the treatment of atrophic and hypertrophic scars in a systematic review. The database was searched, and 10 articles were selected that were relevant in terms of content, topic, and purpose and met the inclusion criteria. Of all the articles reviewed in this study, there were 2 randomized split-face trials (20%), 1 controlled nonrandomized trial (10%), 1 controlled randomized phase III clinical trial (10%), 1 prospective trial (10%), 1 prospective nonrandomized open-label trial (10%), and 1 randomized comparative trial (10%), with the type of study not reported in 3 articles. We used Endnote X8 to review the articles and extract data. After review, the studies were analyzed and categorized. No statistically significant difference was found between the two methods, laser and micro-needling, in the treatment of atrophic and hypertrophic scars in 60% of the articles studied, and both showed significant improvement (70% or more improvement to complete response). Significant improvement was noted in 20% of the studies reviewed for the laser and micro-needling treatment methods. The results of this study show that needling and ablative fractional lasers are tolerable and safe procedures with no significant difference in the treatment of skin scars in sixty percent of the studies.

摘要

本研究旨在通过系统评价比较针刺疗法(射频针刺、中胚层针刺、微针)和剥脱性点阵激光(二氧化碳、铒钇铝石榴石)治疗萎缩性和增生性瘢痕的效果。对数据库进行了检索,筛选出10篇在内容、主题和目的方面相关且符合纳入标准的文章。在本研究中回顾的所有文章中,有2项随机半脸对照试验(20%)、1项非随机对照试验(10%)、1项随机对照III期临床试验(10%)、1项前瞻性试验(10%)、1项前瞻性非随机开放标签试验(10%)和1项随机对照试验(10%),3篇文章未报告研究类型。我们使用Endnote X8对文章进行回顾并提取数据。回顾后,对研究进行分析和分类。在60%的研究文章中,激光和微针两种方法在治疗萎缩性和增生性瘢痕方面未发现统计学上的显著差异,且两者均显示出显著改善(改善70%或更多至完全缓解)。在20%的回顾研究中,激光和微针治疗方法均有显著改善。本研究结果表明,在60%的研究中,针刺疗法和剥脱性点阵激光是可耐受且安全的治疗方法,在治疗皮肤瘢痕方面无显著差异。

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