Melmer Andreas, Laimer Markus
Endocr Dev. 2016;31:1-27. doi: 10.1159/000439364. Epub 2016 Jan 19.
The quality of glycaemic control in diabetes mellitus relies on accurate individualization of available treatment options. Treatment targets depend on the type and duration of diabetes, the patients' abilities and characteristics and the individual risk for acute and/or late-stage complications. These complications include hypoglycaemia, which can be severe and life threatening, hyperglycaemia, which is a main factor for the development of cardiovascular disease, and macrovascular and microvascular disease, both of which are hallmark features of diabetes-associated constraints. Moreover, other treatment goals in diabetic patients influence both glycaemic control and quality of life. Lipoproteins, blood pressure, weight control, mental health and lifestyle are important factors that contribute to the frequency of diabetes-associated complications.
糖尿病的血糖控制质量依赖于对现有治疗方案进行准确的个体化。治疗目标取决于糖尿病的类型和病程、患者的能力及特征以及急性和/或晚期并发症的个体风险。这些并发症包括可能严重且危及生命的低血糖、作为心血管疾病发生主要因素的高血糖以及大血管和微血管疾病，这两种疾病都是糖尿病相关限制的标志性特征。此外，糖尿病患者的其他治疗目标会影响血糖控制和生活质量。脂蛋白、血压、体重控制、心理健康和生活方式都是导致糖尿病相关并发症发生频率的重要因素。
