Yang Jiangwei, Liang Xinyi, Cui Lan, Liu Haiyan, Xie Junbo, Liu Weixing
Tianjin Key Laboratory of Food and Biotechnology, Department of Applied Chemistry, College of Science, Tianjin University of Commerce, Tianjin 300134, PR China.
Tianjin Key Laboratory of Food and Biotechnology, Department of Applied Chemistry, College of Science, Tianjin University of Commerce, Tianjin 300134, PR China.
Biosens Bioelectron. 2016 Jun 15;80:171-174. doi: 10.1016/j.bios.2016.01.056. Epub 2016 Jan 22.
A novel non-enzymatic glucose sensor based on a glassy carbon electrode modified with Pt3Ru1 alloy nanoparticles (Pt3Ru1/GCE) was fabricated. Pt3Ru1 alloy nanoparticles were prepared by a reverse microemulsion method at room temperature. The X-ray diffraction (XRD) and energy dispersive X-ray spectroscopy (EDS) demonstrate that Pt3Ru1 nanoparticles are disordered alloy with face central cubic (fcc) structure and the atom ratio of Pt and Ru is 3:1. The high-resolution transmission electron microscopy (HRTEM) images show that Pt3Ru1 alloy nanoparticles were aggregated with a high density of surface defects. Furthermore, the sensor properties of Pt3Ru1/GCE were investigated by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and chronoamperometry (CA) in 0.01 M PBS (pH 7.4). The results indicate that the proposed sensor exhibits a wide linear range of 5 × 10(-7)M to 10(-2)M (R(2)=0.9988) with a low detection limit of 0.3 μM for glucose. Moreover, the sensor demonstrates good sensitivity, stability, reproducibility, and better anti-interference performance toward ascorbic acid (AA), uric acid (UA), and fructose (Fru).
制备了一种基于用Pt3Ru1合金纳米颗粒修饰的玻碳电极（Pt3Ru1/GCE）的新型非酶葡萄糖传感器。Pt3Ru1合金纳米颗粒在室温下通过反相微乳液法制备。X射线衍射（XRD）和能量色散X射线光谱（EDS）表明，Pt3Ru1纳米颗粒是具有面心立方（fcc）结构的无序合金，Pt和Ru的原子比为3:1。高分辨率透射电子显微镜（HRTEM）图像显示，Pt3Ru1合金纳米颗粒聚集在一起，表面缺陷密度高。此外，通过循环伏安法（CV）、电化学阻抗谱（EIS）和计时电流法（CA）在0.01 M PBS（pH 7.4）中研究了Pt3Ru1/GCE的传感器性能。结果表明，所提出的传感器对葡萄糖具有5×10(-7)M至10(-2)M的宽线性范围（R(2)=0.9988），检测限低至0.3 μM。此外，该传感器表现出良好的灵敏度、稳定性、重现性，并且对抗坏血酸（AA）、尿酸（UA）和果糖（Fru）具有更好的抗干扰性能。
