Şahin Muhammed, Yüksel Harun, Şahin Alparslan, Cingü Abdullah Kürşat, Türkcü Fatih Mehmet, Kaya Savaş, Yazmalar Levent, Batmaz İbrahim
a School of Medicine, Department of Ophthalmology , Dicle University , Diyarbakir , Turkey.
b Department of Immunology , Dicle University , Diyarbakir , Turkey.
Ocul Immunol Inflamm. 2017 Apr;25(2):233-238. doi: 10.3109/09273948.2015.1115079. Epub 2016 Jan 30.
To evaluate corneal parameters of scleroderma (SC) patients by Pentacam-HR.
Twenty-two eyes of 22 SC patients and 33 eyes of 33 control subjects were enrolled. All participants underwent Pentacam (Pentacam-HR, Oculus, Germany) evaluation. Both SC and control groups were divided into two subgroups as dry eye (DE) (Schirmer test with topical anesthesia (STA) ˂5 mm) and without DE (STA ˃5 mm).
Pachymetric measurements and mean corneal volume (CV) were significantly lower in the SC group than in the control group (p<0.001). Pachymetric measurements and CV of SC patients with DE were significantly lower than all the other subgroups. Control subgroups with or without DE were similar in pachymetric measurements and CV.
The results suggest that SC patients have thinner corneas compared with control subjects. Additionally, coexistence of DE seems to have an additional impact in the thinning of cornea in SC patients.
通过Pentacam-HR评估硬皮病（SC）患者的角膜参数。
纳入22例SC患者的22只眼和33例对照者的33只眼。所有参与者均接受Pentacam（Pentacam-HR，德国Oculus公司）评估。SC组和对照组均分为干眼（DE）（表面麻醉下泪液分泌试验（STA）＜5mm）和无干眼（STA＞5mm）两个亚组。
SC组的角膜厚度测量值和平均角膜容积（CV）显著低于对照组（p＜0.001）。伴有DE的SC患者的角膜厚度测量值和CV显著低于所有其他亚组。有或无DE的对照亚组在角膜厚度测量值和CV方面相似。
结果表明，与对照者相比，SC患者的角膜更薄。此外，DE的共存似乎对SC患者角膜变薄有额外影响。
