Kouris Anargyros, Christodoulou Christos, Efstathiou Vasiliki, Tsatovidou Revekka, Torlidi-Kordera Evangelia, Zouridaki Eftychia, Kontochristopoulos George
Department of Dermatology and Venereology, "Andreas Sygros" Skin Hospital, Athens, Greece.
2nd Department of Psychiatry, "Attikon" University Hospital, Athens, Greece.
Wound Repair Regen. 2016 Mar;24(2):443-6. doi: 10.1111/wrr.12416. Epub 2016 Mar 2.
Psoriasis and leg ulcers have a marked impact on the patient's quality of life and represent a life-long burden for affected patients. The aim of this study is to compare the quality of life, anxiety and depression, self-esteem, and loneliness in patients with psoriasis and leg-ulcer patients. Eighty patients with leg ulcers, eighty patients with psoriasis, and eighty healthy controls were included in this study. The quality of life, depression and anxiety, loneliness of the patient, and self-esteem were assessed using the Dermatology Life Quality Index (DLQI), Hospital Anxiety and Depression Scale (HADS), the UCLA loneliness Scale (UCLA-Version 3), and the Rosenberg's Self-esteem Scale (RSES), respectively. The DLQI score among patients with psoriasis was 12.74 ± 4.89 and leg ulcer patients was 13.28 ± 2.57. The patients with psoriasis presented statistically significant higher anxiety (9.87 ± 4.56) than both leg ulcer patients (8.26 ± 2.82) and controls (6.45 ± 1.89), while leg ulcer patients also presented higher anxiety than controls. Regarding self-esteem, although there were no significant differences between the patients with psoriasis (15.25 ± 3.20) and the ones with leg ulcers (15.89 ± 2.93), they both presented statistically significant lower self-esteem scores than control group (18.53 ± 3.04). The patients with psoriasis presented statistically significant higher levels of loneliness and social isolation (46.18 ± 6.63) compared to leg ulcer patients (43.73 ± 5.68) than controls (42.49 ± 3.41). Psoriasis and leg ulcers are long-term skin diseases associated with significant impairment of the patient's quality of life, anxiety, and self-esteem, which are frequently under-recognized.
银屑病和腿部溃疡对患者的生活质量有显著影响，给受影响的患者带来终身负担。本研究的目的是比较银屑病患者和腿部溃疡患者的生活质量、焦虑和抑郁、自尊及孤独感。本研究纳入了80例腿部溃疡患者、80例银屑病患者和80名健康对照者。分别使用皮肤病生活质量指数（DLQI）、医院焦虑抑郁量表（HADS）、加州大学洛杉矶分校孤独感量表（UCLA-第3版）和罗森伯格自尊量表（RSES）评估患者的生活质量、抑郁和焦虑、孤独感及自尊。银屑病患者的DLQI评分为12.74±4.89，腿部溃疡患者为13.28±2.57。银屑病患者的焦虑程度（9.87±4.56）在统计学上显著高于腿部溃疡患者（8.26±2.82）和对照组（6.45±1.89），而腿部溃疡患者的焦虑程度也高于对照组。关于自尊，虽然银屑病患者（15.25±3.20）和腿部溃疡患者（15.89±2.93）之间没有显著差异，但他们的自尊得分在统计学上均显著低于对照组（18.53±3.04）。与腿部溃疡患者（43.73±5.68）和对照组（42.49±3.41）相比，银屑病患者的孤独感和社会隔离程度在统计学上显著更高（46.18±6.63）。银屑病和腿部溃疡是长期皮肤病，会严重损害患者的生活质量、导致焦虑和自尊问题，这些问题常常未得到充分认识。
