Vasilenko R N, Kondakov K E, Semenkova L N, Denisov L A, Galaktionov V G
Zh Mikrobiol Epidemiol Immunobiol. 1989 Dec(12):54-7.
The influence of human recombinant alpha-interferon (reaferon) on cell-mediated and humoral immune response has been studied. Experimental facts on the blast transformation of lymphocytes, humoral immune response and the reaction of delayed hypersensitivity are presented. The study has shown that reaferon possesses the main immunoregulatory properties, characteristic of natural human leukocytic alpha-interferon. Manifestation of these properties depends on the dose of preparation and the time of its use.
已对重组人α干扰素(利福隆)对细胞介导免疫和体液免疫反应的影响进行了研究。文中给出了关于淋巴细胞增殖转化、体液免疫反应及迟发型超敏反应的实验事实。研究表明,利福隆具有天然人白细胞α干扰素所特有的主要免疫调节特性。这些特性的表现取决于制剂的剂量及其使用时间。