Department of Life and Reproduction Sciences, Pediatrics Section, University of Verona, Verona, Italy.
Transl Pediatr. 2016 Jan;5(1):31-6. doi: 10.3978/j.issn.2224-4336.2015.12.01.
Recurrent wheezing have a significant morbidity and it's estimated that about one third of school-age children manifest the symptom during the first 5 years of life. Proper identification of children at risk of developing asthma at school age may predict long-term outcomes and improve treatment and preventive approach, but the possibility to identify these children at preschool age remains limited. For many years authors focused their studies to identify early children with recurrent wheezing at risk to develop asthma at school age. Different phenotypes have been proposed for a more precise characterization and a personalized plan of treatment. The main criticism concerns the inability to define stable phenotypes with the risk of overestimating or underestimating the characteristics of symptoms in these children. The aim of this review is to report the recent developments on the diagnosis and treatment of recurrent paediatric wheezing.
反复喘息会导致相当高的发病率，据估计，大约三分之一的学龄儿童在生命的头 5 年会出现这种症状。正确识别有发展为哮喘风险的学龄儿童可能有助于预测长期结果，并改善治疗和预防方法，但在学龄前识别这些儿童的可能性仍然有限。多年来，作者们专注于研究，以确定有反复喘息的学龄前儿童是否有发展为学龄期哮喘的风险。为了更精确地描述和制定个性化的治疗方案，提出了不同的表型。主要的批评意见是无法确定稳定的表型，这可能会高估或低估这些儿童症状的特征。本综述旨在报告反复性小儿喘息的诊断和治疗的最新进展。
