Gu Wangyang, Xie Dan, Li Qinpeng, Feng Huike, Xue Yihao, Chen Yang, Tang Jingyi, Zhou Yushi, Wang Dan, Tong Shilu, Liu Shijian
Department of Big Data Center, Sanya Women and Children's Hospital Affiliated to Hainan Medical University, Sanya, China.
Hainan Branch, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Sanya, China.
Front Allergy. 2024 Dec 6;5:1483430. doi: 10.3389/falgy.2024.1483430. eCollection 2024.
The relationship of asthma with humidity and precipitation remains controversial. The objective of this study was to investigate the association of increased humidity and precipitation with asthma risk.
A comprehensive systematic search was conducted across various databases, including PubMed, Embase, Cochrane Library, Web of Science, Chinese Wanfang, CQVIP, and CNKI. A total of 21 studies with 1,052,960 participants from 9 countries or regions were included. The fixed and random effect model were used to analyze the data.
The study revealed a pooled odds ratio (OR) of 1.0489 [95% confidence interval (CI): 1.0061, 1.0935] for the association between humidity and asthma risk. Specifically, among individuals under 18 years of age, the OR (95% CI) was 1.0898 (1.0290, 1.1541). Furthermore, the OR (95% CI) for developing countries or regions was 1.0927 (1.0220, 1.1684), while it was 1.1298 (0.9502, 1.3433) for regions with a high latitude (41°-51°). The pooled OR for precipitation and asthma risk was 0.9991 (0.9987, 0.9995). The OR (95%CI) values were 0.9991 (0.9987, 0.9995), 0.9991 (0.9987, 0.9995) and 0.9990 (0.9986, 0.9994) in people above the age of 18, developing countries or regions, and middle latitudes (31°-41°), respectively.
The impact of humidity on asthma risk is particularly pronounced among individuals below 18 years of age, people living in developing countries or regions and in regions located in high latitudes. And the influence of precipitation on asthma persons over the age of 18, developing countries or regions, and middle latitudes significantly. Increased humidity appears to elevate asthma risk, and increased precipitation may reduce the risk. In addition, there appears to be a combined effect of humidity and precipitation on asthma.
PROSPERO, identifier, CRD42023482446.
哮喘与湿度和降水之间的关系仍存在争议。本研究的目的是调查湿度增加和降水与哮喘风险之间的关联。
对多个数据库进行了全面系统的检索，包括PubMed、Embase、Cochrane图书馆、科学网、中国万方、维普资讯和中国知网。共纳入了来自9个国家或地区的21项研究，涉及1,052,960名参与者。采用固定效应模型和随机效应模型对数据进行分析。
研究显示，湿度与哮喘风险之间关联的合并比值比（OR）为1.0489 [95%置信区间（CI）：1.0061, 1.0935]。具体而言，在18岁以下的个体中，OR（95%CI）为1.0898（1.0290, 1.1541）。此外，发展中国家或地区的OR（95%CI）为1.0927（1.0220, 1.1684），而高纬度地区（41°-51°）的OR为1.1298（0.9502, 1.3433）。降水与哮喘风险的合并OR为0.9991（0.9987, 0.9995）。在18岁以上人群、发展中国家或地区以及中纬度地区（31°-41°），OR（95%CI）值分别为0.9991（0.9987, 0.9995）、0.9991（0.9987, 0.9995）和0.9990（0.9986, 0.9994）。
湿度对哮喘风险的影响在18岁以下个体、生活在发展中国家或地区以及高纬度地区的人群中尤为明显。降水对18岁以上人群、发展中国家或地区以及中纬度地区的哮喘患者有显著影响。湿度增加似乎会提高哮喘风险，而降水增加可能会降低风险。此外，湿度和降水对哮喘似乎存在综合影响。
PROSPERO，标识符，CRD42023482446。
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