Division of Allergy and Immunology, Boston Children's Hospital, Boston, MA, U.S.
Asian Pac J Allergy Immunol. 2014 Jun;32(2):103-10.
Exposure to indoor pollutants and allergens has been speculated to cause asthma symptoms and exacerbations and influence the risk of developing asthma. The aim of this article is to review the medical literature regarding the role of the indoor environment on inner-city childhood asthma.
A literature search was performed in PubMed. Studies focusing on inner-city indoor allergen, childhood asthma, and environmental controls were included.
The prevalence of asthma in children is increasing especially in inner-city area. Exposure to high levels of indoor allergens and pollutants has been related to asthma development. Studies have shown that mouse, cockroach, pets, dust mite, mold, tobacco smoke, endotoxin and nitrogen dioxide are the important exposures. Recent studies have shown that indoor environmental control is beneficial in reducing asthma morbidity and development.
Inner-city children are exposed to various indoor allergens and pollutants that may lead to asthma development and exacerbation of existing asthma. Multifaceted environmental controls are beneficial in improving asthma symptom and maybe a viable prevention strategy. Further prospective studies of environmental intervention are needed to further identify effective strategies to improve and prevent asthma symptoms in inner-city children.
室内污染物和过敏原的暴露被认为会导致哮喘症状和加重，并影响哮喘的发病风险。本文旨在回顾有关室内环境对城市内儿童哮喘影响的医学文献。
在 PubMed 上进行了文献检索。纳入了专注于城市内室内过敏原、儿童哮喘和环境控制的研究。
儿童哮喘的患病率呈上升趋势，尤其是在城市地区。高水平的室内过敏原和污染物暴露与哮喘的发展有关。研究表明，老鼠、蟑螂、宠物、尘螨、霉菌、烟草烟雾、内毒素和二氧化氮是重要的暴露源。最近的研究表明，室内环境控制有助于降低哮喘发病率和病情加重。
城市内儿童会接触到各种室内过敏原和污染物，这可能导致哮喘的发展和现有哮喘的加重。多方面的环境控制有助于改善哮喘症状，可能是一种可行的预防策略。需要进一步开展环境干预的前瞻性研究，以进一步确定改善和预防城市内儿童哮喘症状的有效策略。
