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阿尔茨海默病患者吞咽困难的诊断评估与管理

Diagnostic Assessment and Management of Dysphagia in Patients with Alzheimer's Disease.

作者信息

Boccardi Virginia, Ruggiero Carmelinda, Patriti Alberto, Marano Luigi

机构信息

Institute of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy.

General, Minimally Invasive and Robotic Surgery, Department of Surgery, "San Matteo degli Infermi" Hospital, ASL Umbria 2, Spoleto, Italy.

出版信息

J Alzheimers Dis. 2016;50(4):947-55. doi: 10.3233/JAD-150931.

DOI:10.3233/JAD-150931
PMID:26836016
Abstract

A growing concern in patients affected by Alzheimer's disease (AD) is dysphagia, or swallowing impairment, which leads to malnutrition, dehydration, weight loss, functional decline and fear of eating and drinking, as well as a decrease in the quality of life. Thus the diagnostic assessment of dysphagia in patients with AD is imperative to ensure that they receive effective management, avoiding complications, and reducing comorbidity and mortality in such a growing population. Dysphagia management requires a multidisciplinary approach considering that no single strategy is appropriate for all patients. However, evidence for clinical diagnostic assessment, interventions, and medical management of dysphagia in these patients are still limited: few studies are reporting the evaluation and the management among this group of patients. Here we analyzed the most recent findings in diagnostic assessment and management of swallowing impairment in patients affected by AD.

摘要

阿尔茨海默病(AD)患者日益受到关注的一个问题是吞咽困难,即吞咽功能受损,这会导致营养不良、脱水、体重减轻、功能衰退以及对饮食的恐惧,同时还会降低生活质量。因此,对AD患者的吞咽困难进行诊断评估至关重要,以确保他们得到有效的管理,避免并发症,并降低这一不断增长的人群中的合并症和死亡率。吞咽困难的管理需要多学科方法,因为没有单一策略适用于所有患者。然而,关于这些患者吞咽困难的临床诊断评估、干预措施和医学管理的证据仍然有限:很少有研究报告这组患者的评估和管理情况。在此,我们分析了AD患者吞咽障碍诊断评估和管理的最新研究结果。

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