早期种植失败的风险因素：一项荟萃分析。
Risk Factors in Early Implant Failure: A Meta-Analysis.
作者信息
Manzano Guillermo, Montero Javier, Martín-Vallejo Javier, Del Fabbro Massimo, Bravo Manuel, Testori Tiziano
机构信息
*Postgraduate Student, Master in Dental Sciences, University of Salamanca (USAL), Salamanca, Spain. †Tenured Lecturer in Prosthodontics, Department of Surgery, Faculty of Medicine, University of Salamanca (USAL), Salamanca, Spain. ‡Tenured Lecturer in Statistics, Department of Statistics, School of Nursing, University of Salamanca (USAL), Salamanca, Spain. §Associate Professor, Head of Section of Oral Physiology, Department of Biomedical, Surgical and Dental Sciences, IRCCS Galeazzi Institute, University of Milan, Milan, Italy. ¶Professor of Preventive and Community Dentistry, Faculty of Odontology, University of Granada, Granada, Spain. ‖Visiting Professor, Head of the Section of Implant Dentistry and Oral Rehabilitation, Department of Biomedical, Surgical, and Dental Sciences, Dental Clinic (Chairman: Prof. R.L. Weinstein), IRCCS Galeazzi Institute, University of Milan, Milan, Italy.
出版信息
Implant Dent. 2016 Apr;25(2):272-80. doi: 10.1097/ID.0000000000000386.
BACKGROUND
Clinicians should be able to weigh the role of the main risk factors associated with early implant failure.
PURPOSE
The aim of this meta-analysis was to assess the influence of different patient-related and implant-related risk factors on the occurrence of early implant failure.
MATERIALS AND METHODS
In July, 2014 the main electronic databases were searched for studies reporting on early failures. Relevant papers were selected by 2 independent authors using predefined selection criteria. Three authors independently scored the included studies for quality assessment. The estimated odds ratios of the main risk factors from the selected papers were subjected to meta-analysis.
RESULTS
Nine studies were included. A total of 18,171 implants were meta-analyzed, of which 10,921 were analyzed for smoking, 15,260 for implant diameter, 16,075 for implant length, and 16,711 for implant location (maxilla vs mandible). The main significant risk factors for early implant failures were the smoking habit (odds ratio [OR], 1.7; 95% confidence interval [CI], 1.3, 2.3), implants shorter than 10 mm (OR, 1.6; 95% CI, 1.2, 2.2) and implants placed in the maxilla (OR, 1.3; 95% CI, 1.0, 1.6).
CONCLUSIONS
Clinicians should be aware of the increased risk of early failure in the presence of smokers, implants with reduced length, and implant-supported maxillary rehabilitation.
背景
临床医生应能够权衡与早期种植失败相关的主要风险因素的作用。
目的
本荟萃分析的目的是评估不同的患者相关和种植体相关风险因素对早期种植失败发生的影响。
材料与方法
2014年7月检索主要电子数据库，查找关于早期失败的研究报告。由2名独立作者根据预先确定的选择标准选择相关论文。3名作者独立对纳入研究进行质量评估评分。对所选论文中主要风险因素的估计比值比进行荟萃分析。
结果
纳入9项研究。共对18171颗种植体进行了荟萃分析，其中10921颗分析了吸烟情况，15260颗分析了种植体直径，16075颗分析了种植体长度，16711颗分析了种植体位置（上颌与下颌）。早期种植失败的主要显著风险因素为吸烟习惯（比值比[OR]，1.7；95%置信区间[CI]，1.3，2.3）、长度小于10 mm的种植体（OR，1.6；95%CI，1.2，2.2）以及上颌种植体（OR，1.3；95%CI，1.0，1.6）。
结论
临床医生应意识到，吸烟者、长度较短的种植体以及上颌种植支持修复存在早期失败风险增加的情况。
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