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义齿引导下的口腔种植手术。一项评估5年手术结果的回顾性队列研究。

Prosthetically guided oral implant surgery. A retrospective cohort study evaluating the 5-year surgical outcome.

作者信息

Sakkas Andreas, Westendorf Stefan, Thiele Oliver Christian, Schramm Alexander, Wilde Frank, Pietzka Sebastian

机构信息

Department of Cranio-Maxillo-Facial-Surgery, German Armed Forces Hospital Ulm, Germany.

Department of Cranio-Maxillo-Facial-Surgery, University Hospital Ulm, Germany.

出版信息

GMS Interdiscip Plast Reconstr Surg DGPW. 2023 Aug 18;12:Doc06. doi: 10.3205/iprs000176. eCollection 2023.

DOI:10.3205/iprs000176
PMID:37693294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10486885/
Abstract

PURPOSE

This study primarily evaluated the 5-year implant survival and success rate of prosthetically guided inserted implants. The secondary aim was to evaluate the impact of clinical variables on the development of mucositis, peri-implant bone resorption, peri-implantitis, as well as early and late implant failure.

MATERIALS AND METHODS

An observational retrospective single-centre study was conducted on patients who were treated with dental implants in the department of oral and plastic maxillofacial surgery of the military hospital of Ulm University between 2008 and 2010. In all patients, computer-assisted 3D planning after wax-up of the prosthetic restoration and template-guided surgery with titanium implants were performed. Bone augmentation procedures were performed primarily if needed. Intraoperative and postoperative complications as well as technical and mechanical complications after prosthesis loading were evaluated. In a 5-year clinical and radiological follow-up, implant success and implant survival were assessed using descriptive statistics. A multivariable regression analysis evaluated the potential impact of augmentation procedures, wound healing complications, smoking, history of periodontitis, and preoperative API (approximal plaque index) and SBI (sulcus bleeding index) values on peri-implant mucositis, peri-implant bone resorption, peri-implantitis, as well as early and late implant failure.

RESULTS

In this study, 466 implants in 283 patients were considered for inclusion, and sufficient data were obtained for analysis from 368 (78.9%) implants in 229 (80.9%) patients. An overall implant survival rate of 98.1% (n=361/368) at the 5-year follow-up was revealed. According to the success criteria of the study, the 5-year success rate was 97.04% (n=263/271). An early implant failure of 1.07% (n=5/466) was recorded. 48.2% of the implants were affected by peri-implant mucositis (n=122/253), while peri-implant bone resorption was detected in 21.7% of the radiologically examined implants (n=59/271). Fifteen cases of peri-implantitis (5.5%) were detected. Peri-implant bone resorption increased significantly after bone augmentation procedures (p=0.028). Wound healing complications after implantation significantly increased the prevalence of late implant failure in the maxilla (p<0.001). Peri-implant bone resorption and peri-implantitis were significantly more prevalent in smokers (p=0.022/p=0.043). Implants in patients with API>20% presented significantly higher rates of peri-implant mucositis (p=0.042). Wound healing complications after augmentation, history of periodontitis, and SBI>20% had no significant impact on the study parameters.

CONCLUSIONS

The study confirms the reliability of prosthetically guided implant surgery, showing a high implant survival and success rate in a 5-year follow-up. Intraoperative complications and technical or mechanical complications after prosthesis loading remain within acceptable clinical limits. The rate of peri-implant mucositis, peri-implant bone resorption, and peri-implantitis was within the current literature range. Optimizing periodontal health and reducing smoking would improve the outcome. Further studies need to clarify the clinical indications and investigate the long-term surgical outcome of this treatment concept.

摘要

目的

本研究主要评估了修复引导下植入种植体的5年种植体存留率和成功率。次要目的是评估临床变量对种植体周围黏膜炎、种植体周围骨吸收、种植体周围炎以及种植体早期和晚期失败的影响。

材料与方法

对2008年至2010年在乌尔姆大学军事医院口腔颌面整形外科接受牙种植治疗的患者进行了一项观察性回顾性单中心研究。所有患者均进行了修复体蜡型后的计算机辅助三维规划以及钛种植体的模板引导手术。如有需要,主要进行骨增量手术。评估了术中及术后并发症以及修复体加载后的技术和机械并发症。在5年的临床和影像学随访中,使用描述性统计评估种植体的成功率和存留率。多变量回归分析评估了骨增量手术、伤口愈合并发症、吸烟、牙周炎病史以及术前邻面菌斑指数(API)和龈沟出血指数(SBI)值对种植体周围黏膜炎、种植体周围骨吸收、种植体周围炎以及种植体早期和晚期失败的潜在影响。

结果

本研究纳入了283例患者的466枚种植体,从229例(80.9%)患者的368枚(78.9%)种植体中获得了足够的分析数据。5年随访时总体种植体存留率为98.1%(n = 361/368)。根据研究的成功标准,5年成功率为97.04%(n = 263/271)。记录到早期种植体失败率为1.07%(n = 5/466)。48.2%的种植体受到种植体周围黏膜炎影响(n = 122/253),而在影像学检查的种植体中,21.7%检测到种植体周围骨吸收(n = 59/271)。检测到15例种植体周围炎(5.5%)。骨增量手术后种植体周围骨吸收显著增加(p = 0.028)。植入后伤口愈合并发症显著增加了上颌种植体晚期失败的发生率(p < 0.001)。吸烟者种植体周围骨吸收和种植体周围炎的发生率显著更高(p = 0.022/p = 0.043)。API>20%患者的种植体周围黏膜炎发生率显著更高(p = 0.042)。骨增量后的伤口愈合并发症、牙周炎病史以及SBI>20%对研究参数无显著影响。

结论

本研究证实了修复引导下种植手术的可靠性,在5年随访中显示出高种植体存留率和成功率。术中并发症以及修复体加载后的技术或机械并发症仍在可接受的临床范围内。种植体周围黏膜炎、种植体周围骨吸收和种植体周围炎的发生率在当前文献范围内。优化牙周健康和减少吸烟将改善治疗结果。进一步的研究需要明确临床适应证并调查该治疗理念的长期手术效果。

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