Reid G, Kumar H, Khan A I, Rautava S, Tobin J, Salminen S
1 Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, 268 Grosvenor Street, London, Ontario N6A 4V2, Canada.
2 Department of Microbiology and Immunology, University of Western Ontario, London, Ontario N6A 5C1, Canada.
Benef Microbes. 2016 Jun;7(3):353-62. doi: 10.3920/BM2015.0140. Epub 2016 Feb 3.
Successful human reproduction requires microbial homeostasis in the female reproductive tract, and colonisation of the newborn with beneficial microbes. In order to prevent several complications associated with dysbiosis, the administration of probiotics is more often being considered. The objective of the enclosed review was to examine the rationale for probiotic utility before and during pregnancy and in the early phase of infant life. The conclusions emerged from a panel of researchers who met during the International Scientific Association for Probiotics and Prebiotics (ISAPP) workshop held in Washington, DC, USA in 2015. The group concluded based upon the current literature, that a case can be made for the use of a specific sets of probiotic organisms during the first 1,500 days of life, with the goal of a healthy pregnancy to term, and a healthy start to life with lowered risk of infections and inflammatory events. The key to successfully translating these recommendations to practice is that products be made available and affordable to women in developed and developing countries.
人类成功繁殖需要女性生殖道内的微生物稳态，以及新生儿有益微生物的定植。为了预防与生态失调相关的多种并发症，人们越来越多地考虑使用益生菌。本综述的目的是探讨孕期及婴儿早期使用益生菌的理论依据。这些结论来自于2015年在美国华盛顿特区举行的国际益生菌和益生元科学协会（ISAPP）研讨会上会面的一组研究人员。该小组根据现有文献得出结论，认为在生命的前1500天使用特定的益生菌菌株是有依据的，目标是实现健康的足月妊娠，并让生命有一个健康的开端，降低感染和炎症事件的风险。将这些建议成功转化为实际行动的关键在于，要让发达国家和发展中国家的女性都能获得并负担得起相关产品。
