Monitillo Francesco, Leone Marta, Rizzo Caterina, Passantino Andrea, Iacoviello Massimo
Francesco Monitillo, Marta Leone, Caterina Rizzo, Massimo Iacoviello, Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, Italy.
World J Cardiol. 2016 Jan 26;8(1):57-73. doi: 10.4330/wjc.v8.i1.57.
Ventricular repolarization is a complex electrical phenomenon which represents a crucial stage in electrical cardiac activity. It is expressed on the surface electrocardiogram by the interval between the start of the QRS complex and the end of the T wave or U wave (QT). Several physiological, pathological and iatrogenic factors can influence ventricular repolarization. It has been demonstrated that small perturbations in this process can be a potential trigger of malignant arrhythmias, therefore the analysis of ventricular repolarization represents an interesting tool to implement risk stratification of arrhythmic events in different clinical settings. The aim of this review is to critically revise the traditional methods of static analysis of ventricular repolarization as well as those for dynamic evaluation, their prognostic significance and the possible application in daily clinical practice.
心室复极是一种复杂的电现象,它代表着心脏电活动中的一个关键阶段。它在体表心电图上通过QRS波群起始与T波或U波结束之间的间期(QT间期)来体现。多种生理、病理和医源性因素均可影响心室复极。业已证明,该过程中的微小扰动可能是恶性心律失常的潜在触发因素,因此,心室复极分析是在不同临床环境中对心律失常事件进行风险分层的一项有意义的工具。本综述的目的是批判性地审视心室复极的传统静态分析方法以及动态评估方法、它们的预后意义以及在日常临床实践中的可能应用。