Chen Renzheng, Miao Fengbo, Wang Yujia, Lu Tingting, Qin Cheng, Fang Yan, Wang Yabin, Wang Huiquan, Cao Feng
Institute of Geriatric Medicine, Beijing Key Laboratory of Geriatric Comorbidity, National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Department of Cardiology, The Second Medical Center, Chinese PLA General Hospital, Beijing, China.
Sci Rep. 2025 Jul 1;15(1):21827. doi: 10.1038/s41598-025-08569-z.
Cold stress can affect ventricular repolarization (VR), which may serve as a potential trigger for malignant arrhythmias. Compared to conventional electrocardiogram (ECG) devices, wearable technology is more suitable for out-of-hospital monitoring due to their portability. However, outdoor cold environments can limit their application. We aimed to develop a wearable ECG capable of functioning in a cold environment. Moreover, to explore the impact of cold stress on VR parameters in a real-world cold environment and identify associated cardiovascular risks. A self-developed handheld 12-lead wearable ECG was utilized, featuring a fabric electrode and a novel "sandwich" design to enhance its applicability in cold environments. A total of 152 healthy adults were enrolled and both conventional and wearable ECG were performed on them. The results from testing under an outdoor cold environment indicated that the parameters of the ECG measured by the wearable device were in good agreement with those measured by the conventional machine. Those with higher baseline heart rate (HR) were at increased risk of prolonged QT, TpTe and TpTe/QT when compared to those with lower baseline HR after exposure to a cold environment, potentially enabling risk stratification for arrhythmia-prone populations, thereby reducing the incidence of sudden cardiac death.
寒冷应激可影响心室复极（VR），这可能是恶性心律失常的潜在触发因素。与传统心电图（ECG）设备相比，可穿戴技术因其便携性更适合院外监测。然而，户外寒冷环境会限制其应用。我们旨在开发一种能够在寒冷环境中运行的可穿戴式心电图设备。此外，探索寒冷应激在现实世界寒冷环境中对VR参数的影响，并识别相关的心血管风险。使用了一种自行研发的手持式12导联可穿戴式心电图设备，其具有织物电极和新颖的“三明治”设计，以增强其在寒冷环境中的适用性。共招募了152名健康成年人，并对他们进行了传统心电图和可穿戴式心电图检查。在户外寒冷环境下的测试结果表明，可穿戴设备测量的心电图参数与传统机器测量的参数高度一致。与暴露于寒冷环境后基线心率较低的人相比，基线心率（HR）较高的人发生QT间期延长、TpTe和TpTe/QT的风险增加，这可能为易发生心律失常的人群进行风险分层，从而降低心脏性猝死的发生率。
