Estimating the degree of infection of Plasmodium berghei infected red blood cells by evaluation of pyruvate kinase activity.
作者信息
Buckwitz D, Jacobasch G, Break M
机构信息
Institute of Biochemistry, School of Medicine (Charité), Humboldt-University, Berlin, G.D.R.
出版信息
Dis Markers. 1989 Oct-Dec;7(4):229-38.
PMID:2684475
Abstract
A procedure is proposed to estimate the parasitemia of red blood cells infected with P. berghei by determination of pyruvate kinase activity. The activity of this enzyme shows a linear dependence not on the relative number of infected cells but on the average number of parasites per red blood cell. To provide a transformation between these two parameters a theoretical model of multiple infections of blood cells is derived, the accuracy of which was proved experimentally.
摘要
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