一名成人急性髓系白血病之前的双侧眼眶髓系肉瘤：病例报告及文献复习
Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature.
作者信息
Vera-Aguilera Jesus, Mukarram Osama, Nutalapati Prathibha, Mok Mary, Bulumulle Anushi, Vera-Aguilera Carlos
机构信息
Internal Medicine Department, Texas Tech University Health Sciences Center at the Permian Basin, 800 W. 4th Street, Odessa, TX, 79763, USA.
Departamento de Biología Celular y Tisular, Facultad de Medicina, Universidad Nacional Autónoma de México, México City, México.
出版信息
J Med Case Rep. 2016 Feb 4;10:31. doi: 10.1186/s13256-015-0778-2.
BACKGROUND
Acute myeloid leukemia is typically a disease of the older population and presents mostly in the fifth decade of life. Myeloid sarcoma is a rare initial presentation of acute myeloid leukemia. Previously it has only been documented in children and younger patients.
CASE PRESENTATION
We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old Caucasian man, with rearrangement of chromosome 11q23 involving the MLL gene.
CONCLUSIONS
We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old man, with rearrangement of chromosome 11q23 involving the MLL gene.
背景
急性髓系白血病通常是一种老年人群的疾病，大多出现在生命的第五个十年。髓系肉瘤是急性髓系白血病罕见的初始表现形式。此前仅在儿童和年轻患者中有所记载。
病例报告
我们报告一例不寻常的眶后髓系肉瘤病例，该病例为一名43岁白种男性急性髓系白血病的初始表现，伴有涉及MLL基因的11q23染色体重排。
结论
我们报告一例不寻常的眶后髓系肉瘤病例，该病例为一名43岁男性急性髓系白血病的初始表现，伴有涉及MLL基因的11q23染色体重排。
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