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肝移植:术中经食管超声心动图检查结果及其与术后主要不良心脏事件的关系。

Liver Transplantation: Intraoperative Transesophageal Echocardiography Findings and Relationship to Major Postoperative Adverse Cardiac Events.

作者信息

Shillcutt Sasha K, Ringenberg Kyle J, Chacon M Megan, Brakke Tara R, Montzingo Candice R, Lyden Elizabeth R, Schulte Thomas E, Porter Thomas R, Lisco Steven J

机构信息

Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE.

Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE.

出版信息

J Cardiothorac Vasc Anesth. 2016 Jan;30(1):107-14. doi: 10.1053/j.jvca.2015.09.009. Epub 2015 Sep 25.

DOI:10.1053/j.jvca.2015.09.009
PMID:26847749
Abstract

OBJECTIVE

The primary aim of the study was to describe the most common intraoperative transesophageal echocardiography (TEE) findings during the 3 separate phases of orthotopic liver transplantation (OLT). The secondary aim of the study was to determine if the abnormal TEE findings were associated with major postoperative adverse cardiac events (MACE) and thus may be amenable to future management strategies.

DESIGN

Data were collected retrospectively from the electronic medical record and institutional echocardiography database.

SETTING

Single university hospital.

PARTICIPANTS

A total of 100 patients undergoing OLT via total cavaplasty technique.

INTERVENTIONS

Intraoperative TEE was performed in all 3 phases of OLT.

MEASUREMENT AND MAIN RESULTS

TEE findings of 100 patients who had TEE during OLT during the dissection, anhepatic, and reperfusion phases of transplantation were recorded after blind review. Findings then were analyzed to see if those findings were predictive of postoperative MACE. Intraoperative TEE findings varied among the different phases of OLT. Common TEE findings at reperfusion were microemboli (n = 40, 40%), isolated right ventricular dysfunction (n = 22, 22%), and intracardiac thromboemboli (n = 20, 20%).

CONCLUSIONS

Intraoperative echocardiography findings during liver transplantation varied during each phase of transplantation. The presence of intracardiac thromboemboli or biventricular dysfunction on intraoperative echocardiography was predictive of short- and long-term major postoperative adverse cardiac events.

摘要

目的

本研究的主要目的是描述原位肝移植(OLT)三个不同阶段中最常见的术中经食管超声心动图(TEE)检查结果。本研究的次要目的是确定TEE异常检查结果是否与术后主要不良心脏事件(MACE)相关,从而是否适用于未来的管理策略。

设计

从电子病历和机构超声心动图数据库中回顾性收集数据。

地点

单一大学医院。

参与者

总共100例通过全腔静脉成形术技术接受OLT的患者。

干预措施

在OLT的所有三个阶段均进行术中TEE检查。

测量和主要结果

在盲法评估后记录了100例在OLT手术的解剖、无肝和再灌注阶段接受TEE检查的患者的TEE检查结果。然后对结果进行分析,以查看这些结果是否可预测术后MACE。术中TEE检查结果在OLT的不同阶段有所不同。再灌注时常见的TEE检查结果为微栓子(n = 40,40%)、孤立性右心室功能障碍(n = 22,22%)和心内血栓栓塞(n = 20,20%)。

结论

肝移植术中超声心动图检查结果在移植的每个阶段都有所不同。术中超声心动图检查发现心内血栓栓塞或双心室功能障碍可预测术后短期和长期的主要不良心脏事件。

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