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Acidic Water Bathing Could Be a Safe and Effective Therapeutic Modality for Severe and Refractory Atopic Dermatitis.

作者信息

Lee Noo Ri, Lee Hae-Jin, Yoon Na Young, Kim Donghye, Jung Minyoung, Choi Eung Ho

机构信息

Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea.

出版信息

Ann Dermatol. 2016 Feb;28(1):126-9. doi: 10.5021/ad.2016.28.1.126. Epub 2016 Jan 28.

DOI:10.5021/ad.2016.28.1.126
PMID:26848237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4737823/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39cc/4737823/29f2795357c9/ad-28-126-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39cc/4737823/d86fb5d4305c/ad-28-126-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39cc/4737823/29f2795357c9/ad-28-126-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39cc/4737823/d86fb5d4305c/ad-28-126-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39cc/4737823/29f2795357c9/ad-28-126-g002.jpg

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本文引用的文献

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Topical acidic cream prevents the development of atopic dermatitis- and asthma-like lesions in murine model.局部酸性乳膏可预防小鼠模型中特应性皮炎和哮喘样病变的发展。
Exp Dermatol. 2014 Oct;23(10):736-41. doi: 10.1111/exd.12525.
2
Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes.使用多羟基酸使角质层膜结构域急性酸化可改善脂质加工，并抑制角质小体的降解。
J Invest Dermatol. 2010 Feb;130(2):500-10. doi: 10.1038/jid.2009.249. Epub 2009 Sep 10.
3
Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis.
Pediatr Rep. 2024 Jan 8;16(1):57-68. doi: 10.3390/pediatric16010006.
4
Application of Topical Acids Improves Atopic Dermatitis in Murine Model by Enhancement of Skin Barrier Functions Regardless of the Origin of Acids.局部用酸的应用通过增强皮肤屏障功能改善小鼠模型中的特应性皮炎，而与酸的来源无关。
Ann Dermatol. 2016 Dec;28(6):690-696. doi: 10.5021/ad.2016.28.6.690. Epub 2016 Nov 23.
维持角质层酸性可预防小鼠特应性皮炎的发生。
J Invest Dermatol. 2009 Jul;129(7):1824-35. doi: 10.1038/jid.2008.444. Epub 2009 Jan 29.
4
Epidermal sphingolipids: metabolism, function, and roles in skin disorders.表皮鞘脂：代谢、功能及在皮肤疾病中的作用
FEBS Lett. 2006 Oct 9;580(23):5456-66. doi: 10.1016/j.febslet.2006.08.039. Epub 2006 Sep 1.
5
Efficacy and safety of 'wet-wrap' dressings as an intervention treatment in children with severe and/or refractory atopic dermatitis: a critical review of the literature.“湿包裹”敷料作为重度和/或难治性特应性皮炎患儿干预治疗的疗效和安全性：文献综述
Br J Dermatol. 2006 Apr;154(4):579-85. doi: 10.1111/j.1365-2133.2006.07157.x.
6
pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion.pH直接调节表皮通透性屏障的稳态以及角质层的完整性/黏附性。
J Invest Dermatol. 2003 Aug;121(2):345-53. doi: 10.1046/j.1523-1747.2003.12365.x.
7
Treatment of refractory atopic dermatitis using 'wet-wrap' dressings and diluted corticosteroids: results of standardized treatment in both children and adults.使用“湿包裹”敷料和稀释皮质类固醇治疗难治性特应性皮炎：儿童和成人标准化治疗的结果
Dermatology. 2002;204(1):50-5. doi: 10.1159/000051810.
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Generation of free fatty acids from phospholipids regulates stratum corneum acidification and integrity.从磷脂生成游离脂肪酸可调节角质层的酸化和完整性。
J Invest Dermatol. 2001 Jul;117(1):44-51. doi: 10.1046/j.0022-202x.2001.01399.x.
9
Antimicrobial effects of acidic hot-spring water on Staphylococcus aureus strains isolated from atopic dermatitis patients.
J Dermatol Sci. 2000 Nov;24(2):112-8. doi: 10.1016/s0923-1811(00)00091-8.