Jain Ram B
a Private Consultant , Dacula , GA , USA.
Biomarkers. 2016;21(4):342-6. doi: 10.3109/1354750X.2016.1139182. Epub 2016 Feb 5.
Cutoff levels on the scales for benzene, ethylbenzene, toluene, styrene, o-xylene and m/p-xylene in blood were developed to classify smokers from non-smokers. Self-reported smoking during the last 5 d was used as the true smoking status. Receiver operating characteristics methods that minimized the difference between specificity and sensitivity were used to develop these cutoffs. Data from National Health and Nutrition Examination Survey for the cycle 2005-2006 were used for this purpose. For the total population, a cutoff of 0.038 ng/ml for benzene was able to classify smokers from non-smokers with a sensitivity of 83.6% and specificity of 83.7%.
制定了血液中苯、乙苯、甲苯、苯乙烯、邻二甲苯和间/对二甲苯含量的截断水平，以区分吸烟者和非吸烟者。过去5天的自我报告吸烟情况被用作真实吸烟状态。采用使特异性和敏感性差异最小化的受试者工作特征方法来确定这些截断值。为此使用了2005 - 2006年周期的美国国家健康和营养检查调查数据。对于总人口而言，苯的截断值为0.038纳克/毫升时，能够以83.6%的敏感性和83.7%的特异性区分吸烟者和非吸烟者。
