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男性人乳头瘤病毒相关口咽鳞状细胞癌和肛门生殖器癌:关联的流行病学评估

Human papillomavirus-associated oropharyngeal squamous cell carcinoma and anogenital cancers in men: Epidemiologic evaluation of association.

作者信息

Marzouki Hani Z, Biron Vincent L, Harris Jeffrey, O'Connell Daniel, Seikaly Hadi

机构信息

Department of Otolaryngology - Head and Neck Surgery, King Abdulaziz University, Jeddah, Saudi Arabia.

Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

出版信息

Head Neck. 2016 Apr;38 Suppl 1:E2100-2. doi: 10.1002/hed.24388. Epub 2016 Feb 5.

DOI:10.1002/hed.24388
PMID:26849535
Abstract

BACKGROUND

The purpose of this study was to investigate the possible epidemiological association between oropharyngeal carcinoma and anogenital tumors.

METHODS

Population-based demographic and pathologic data on all male patients diagnosed with oropharyngeal squamous cell carcinoma (OPSCC) and anogenital cancer between 1980 and 2011 in the province of Alberta was collected. The risk of association between anogenital cancers and OPSCCs was estimated.

RESULTS

Between 1980 and 2011, a total of 2105 male patients were diagnosed with OPSCC and 914 with anogenital cancers. Only 5 patients were diagnosed with both.

CONCLUSION

In our male population, there was no significant association between anogenital and OPSCCs. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2100-E2102, 2016.

摘要

背景

本研究旨在调查口咽癌与肛门生殖器肿瘤之间可能存在的流行病学关联。

方法

收集了1980年至2011年期间在艾伯塔省被诊断为口咽鳞状细胞癌(OPSCC)和肛门生殖器癌的所有男性患者基于人群的人口统计学和病理数据。估计了肛门生殖器癌与OPSCC之间的关联风险。

结果

1980年至2011年期间,共有2105名男性患者被诊断为OPSCC,914名被诊断为肛门生殖器癌。只有5名患者同时被诊断出这两种疾病。

结论

在我们的男性人群中,肛门生殖器癌与OPSCC之间没有显著关联。©2016威利期刊公司。《头颈》38:E2100 - E2102,2016年。

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J Otolaryngol Head Neck Surg. 2017 Oct 26;46(1):61. doi: 10.1186/s40463-017-0237-8.
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Epigenetics of oropharyngeal squamous cell carcinoma: opportunities for novel chemotherapeutic targets.口咽鳞状细胞癌的表观遗传学:新型化疗靶点的机遇
J Otolaryngol Head Neck Surg. 2017 Jan 31;46(1):9. doi: 10.1186/s40463-017-0185-3.