Wu Haibin, Wang Hao, Hu Ruying, Zhong Jieming, Qian Yijian, Wang Chunmei, Xie Kaixu, Chen Lingli, Gong Weiwei, Guo Yu, Yu Min, Chen Zhengming, Li Liming
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
Tongxiang County Center for Disease Control and Prevention.
Zhonghua Liu Xing Bing Xue Za Zhi. 2015 Nov;36(11):1210-5.
To explore the association between sleep duration and stroke in adults.
Baseline data of 57 704 subjects who were aged 30-79 years and enrolled into China Kadoorie Biobank (CKB) study from Tongxiang county, Zhejiang province were analyzed. Multiple logistic regression analysis was conducted to investigate the putative association between sleep duration and stroke after adjusting for potential confounders.
The mean age of the subjects was (53.15 ± 10.20) years in males and (51.72 ± .69) years in females, respectively. There were 14.43% of males and 15.30% of females reporting sleep durations ≤ 6 hours per day and 5.39% of males and 5.95% of females reporting long duration of sleep (≥ 10 hours per day). The prevalence of stroke was 0.92% in males compared with 0.44% in females. The prevalence of stroke showed a U-shaped distribution with sleep duration. Compared with 7 hours sleep duration per day, long sleep duration (≥ 10 hours per day) was associated with stroke. The odds ratios (OR) were 2.11 (95%CI: 1.32-3.37) for males and 2.13 (95%CI: 1.24-3.65) for females after adjusting for age, socioeconomic status, health behaviors and health status. No statistical significant association was found between short sleep duration and stroke. Meanwhile, frequent sleep snoring was found to be associated with stroke in females (OR=1.63, 95% CI: 1.11-2.40).
Longer sleep duration was found to be associated with higher risk of stroke in both males and females. Frequent sleep snoring would increase the risk of stroke in females.
探讨成年人睡眠时间与中风之间的关联。
分析了来自浙江省桐乡县、年龄在30 - 79岁且纳入中国嘉道理生物样本库（CKB）研究的57704名受试者的基线数据。在调整潜在混杂因素后，进行多因素逻辑回归分析以研究睡眠时间与中风之间的假定关联。
受试者的平均年龄男性为（53.15 ± 10.20）岁，女性为（51.72 ± 10.69）岁。分别有14.43%的男性和15.30%的女性报告每天睡眠时间≤6小时，5.39%的男性和5.95%的女性报告睡眠时间长（≥10小时/天）。男性中风患病率为0.92%，女性为0.44%。中风患病率随睡眠时间呈U形分布。与每天睡眠7小时相比，睡眠时间长（≥10小时/天）与中风有关。在调整年龄、社会经济状况、健康行为和健康状况后，男性的优势比（OR）为2.11（95%CI：1.32 - 3.37），女性为2.13（95%CI：1.24 - 3.65）。未发现短睡眠时间与中风之间存在统计学显著关联。同时，发现女性频繁打鼾与中风有关（OR = 1.63，95%CI：1.11 - 2.40）。
发现睡眠时间较长与男性和女性中风风险较高有关。女性频繁打鼾会增加中风风险。
