Department of Epidemiology and Statistics, School of Public Health, Jilin University, No. 1163 Xinmin Street, Chaoyang District, Changchun, Jilin Province, 130021, China.
Department of Chronic and Non-Communicable Disease Control and Prevention, Sichuan Center for Disease Control and Prevention, No. 6 Zhongxue Road, Wuhou District, Chengdu, Sichuan Province, 610041, China.
BMC Public Health. 2024 Oct 23;24(1):2937. doi: 10.1186/s12889-024-20361-8.
Sleep can function as a potential modifiable risk factor in the control and prevention of stroke. Geography significantly influences sleep patterns. The association of sleep with stroke in population of Southwest China has not so far been investigated.
A total of 55,001 residents aged from 30 to 79 years in Southwest China were included in this study, obtaining their complete information of baseline survey and follow-up in China Kadoorie Biobank (CKB). Sleep-evaluating score was constructed on the basis of short/long sleep duration, insomnia, and snoring. The multivariate Cox proportional hazards regression was used to analyze the association between sleep behaviors and stroke.
During 11.15 years of follow-up, 3410 stroke cases (572.78 cases/100,000 person-years) were documented. There exists no association of sleep-evaluating score with the risk of stroke in the total population. Male-predisposing association between sleep-evaluating score and risk of stroke was observed (for total stroke, HR = 1.52, 95% CI: 1.03-2.23; for hemorrhagic stroke, HR = 2.31, 95% CI: 1.22-4.34), with anisotropism in male residents with overweight and obesity (HR = 1.93, 95% CI: 1.03-3.63), and those without hypertension (HR = 1.76, 95% CI: 1.01-3.07) in the baseline survey.
There exists the male-predisposing association between sleep-evaluating score and the risk of stroke in Southwest China. Improving sleep is required for reducing the risk of stroke.
睡眠可能是控制和预防中风的一个潜在可改变的风险因素。地理因素对睡眠模式有显著影响。睡眠与中国西南部人群中风之间的关系尚未得到研究。
本研究共纳入中国西南地区 55001 名 30-79 岁的居民，获取其在中国慢性病前瞻性研究（CKB）中的基线调查和随访的完整信息。基于短/长睡眠时间、失眠和打鼾构建睡眠评估评分。采用多变量 Cox 比例风险回归分析睡眠行为与中风的关系。
在 11.15 年的随访期间，共记录到 3410 例中风病例（572.78 例/100000 人年）。睡眠评估评分与总人群中风风险之间不存在关联。在男性中观察到睡眠评估评分与中风风险之间存在倾向（总中风，HR=1.52，95%CI：1.03-2.23；出血性中风，HR=2.31，95%CI：1.22-4.34），这种关联在超重和肥胖的男性居民（HR=1.93，95%CI：1.03-3.63）和基线调查中没有高血压的男性居民（HR=1.76，95%CI：1.01-3.07）中存在异质性。
在中国西南部，睡眠评估评分与中风风险之间存在男性倾向关联。改善睡眠是降低中风风险的需要。
