Berber R, Skinner J, Board T, Kendoff D, Eskelinen A, Kwon Y-M, Padgett D E, Hart A
Royal National Orthopaedic Hospital, Brockley Hill, Stanmore Middlesex, HA7 4LP, UK.
Wrightington Hospital, Hall Lane, Appley Bridge, Wrightington, Lancashire, WN6 9EP, UK.
Bone Joint J. 2016 Feb;98-B(2):179-86. doi: 10.1302/0301-620X.98B2.36201.
There are many guidelines that help direct the management of patients with metal-on-metal (MOM) hip arthroplasties. We have undertaken a study to compare the management of patients with MOM hip arthroplasties in different countries.
Six international tertiary referral orthopaedic centres were invited to participate by organising a multi-disciplinary team (MDT) meeting, consisting of two or more revision hip arthroplasty surgeons and a musculoskeletal radiologist. A full clinical dataset including history, blood tests and imaging for ten patients was sent to each unit, for discussion and treatment planning. Differences in the interpretation of findings, management decisions and rationale for decisions were compared using quantitative and qualitative methods.
Overall agreement between the orthopaedic centres and the recommended treatment plans for the ten patients with MOM hip implants was moderate (kappa = 0.6). Full agreement was seen in a third of cases, however split decisions were also seen in a third of cases. Units differed in their interpretation of the significance of the investigation findings and put varying emphasis on serial changes, in the presence of symptoms.
In conclusion, the management of raised or rising blood metal ions, cystic pseudotumours and peri-acetabular osteolysis led to inconsistency in the agreement between centres. Coordinated international guidance and MDT panel discussions are recommended to improve consensus in decision making.
A lack of evidence and the subsequent variation in regulator guidance leads to differences in opinions, the clinical impact of which can be reduced through a multi-disciplinary team approach to managing patients with MOM hip implants. Cite this article: Bone Joint J 2016;98-B:179-86.
有许多指南可指导金属对金属(MOM)髋关节置换患者的管理。我们开展了一项研究,以比较不同国家MOM髋关节置换患者的管理情况。
通过组织一个多学科团队(MDT)会议,邀请了六个国际三级转诊骨科中心参与,该会议由两名或更多的髋关节翻修手术外科医生和一名肌肉骨骼放射科医生组成。向每个单位发送了包括十名患者的病史、血液检查和影像学检查在内的完整临床数据集,用于讨论和治疗计划制定。使用定量和定性方法比较了对检查结果的解读、管理决策以及决策依据方面的差异。
骨科中心之间对于十名MOM髋关节植入患者的总体一致性以及推荐的治疗方案为中等程度(kappa = 0.6)。三分之一的病例达成了完全一致,但也有三分之一的病例出现了不同意见。各单位对检查结果的重要性解读不同,并且在出现症状时对系列变化的重视程度也有所不同。
总之,对于血液中金属离子升高或持续升高、囊性假肿瘤和髋臼周围骨溶解的管理,导致各中心之间的一致性存在差异。建议进行协调一致的国际指导和MDT小组讨论,以提高决策的共识。
缺乏证据以及监管指南随后的差异导致了意见分歧,通过多学科团队方法管理MOM髋关节植入患者可减少其对临床的影响。引用本文:《骨与关节杂志》2016年;98 - B:179 - 86。