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通过整合现有的公共卫生基础设施,在国家免疫规划中成功引入一种未得到充分利用的老年肺炎球菌疫苗。

Successful introduction of an underutilized elderly pneumococcal vaccine in a national immunization program by integrating the pre-existing public health infrastructure.

作者信息

Yang Tae Un, Kim Eunsung, Park Young-Joon, Kim Dongwook, Kwon Yoon Hyung, Shin Jae Kyong, Park Ok

机构信息

Division of Vaccine-Preventable Diseases Control and National Immunization Program, Korea Centers for Disease Control and Prevention, Osong Health Technology Administration Complex, 187 Osongsaengmyeong 2-ro, Osong-eup, Heungduk-gu, Cheongju, Chungcheongbuk-do 363-951, South Korea.

出版信息

Vaccine. 2016 Mar 18;34(13):1623-1629. doi: 10.1016/j.vaccine.2016.01.043. Epub 2016 Feb 3.

Abstract

BACKGROUND

Although pneumococcal vaccines had been recommended for the elderly population in South Korea for a considerable period of time, the coverage has been well below the optimal level. To increase the vaccination rate with integrating the pre-existing public health infrastructure and governmental funding, the Korean government introduced an elderly pneumococcal vaccination into the national immunization program with a 23-valent pneumococcal polysaccharide vaccine in May 2013.

OBJECTIVE

The aim of this study was to assess the performance of the program in increasing the vaccine coverage rate and maintaining stable vaccine supply and safe vaccination during the 20 months of the program.

METHODS

We qualitatively and quantitatively analyzed the process of introducing and the outcomes of the program in terms of the systematic organization, efficiency, and stability at the national level.

RESULTS

A staggered introduction during the first year utilizing the public sector, with a target coverage of 60%, was implemented based on the public demand for an elderly pneumococcal vaccination, vaccine supply capacity, vaccine delivery capacity, safety, and sustainability. During the 20-month program period, the pneumococcal vaccine coverage rate among the population aged ≥65 years increased from 5.0% to 57.3% without a noticeable vaccine shortage or safety issues. A web-based integrated immunization information system, which includes the immunization registry, vaccine supply chain management, and surveillance of adverse events following immunization, reduced programmatic errors and harmonized the overall performance of the program.

CONCLUSION

Introduction of an elderly pneumococcal vaccination in the national immunization program based on strong government commitment, meticulous preparation, financial support, and the pre-existing public health infrastructure resulted in an efficient, stable, and sustainable increase in vaccination coverage.

摘要

背景

尽管韩国在相当长一段时间内一直建议老年人群接种肺炎球菌疫苗,但接种率一直远低于最佳水平。为了通过整合现有的公共卫生基础设施和政府资金来提高接种率,韩国政府于2013年5月将老年肺炎球菌疫苗接种纳入国家免疫规划,使用23价肺炎球菌多糖疫苗。

目的

本研究的目的是评估该规划在20个月期间提高疫苗接种率、维持稳定疫苗供应和安全接种方面的表现。

方法

我们从国家层面的系统组织、效率和稳定性方面,对该规划的引入过程和结果进行了定性和定量分析。

结果

根据公众对老年肺炎球菌疫苗接种的需求、疫苗供应能力、疫苗配送能力、安全性和可持续性,在第一年利用公共部门分阶段引入,目标接种率为60%。在20个月的规划期内,65岁及以上人群的肺炎球菌疫苗接种率从5.0%提高到57.3%,没有出现明显的疫苗短缺或安全问题。一个基于网络的综合免疫信息系统,包括免疫登记、疫苗供应链管理和免疫后不良事件监测,减少了规划性错误,协调了该规划的整体表现。

结论

基于政府的坚定承诺、精心准备、财政支持和现有的公共卫生基础设施,在国家免疫规划中引入老年肺炎球菌疫苗接种,使疫苗接种覆盖率有效、稳定且可持续地提高。

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