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人口结构变化时代的老年人疫苗接种计划。

Vaccination programs for older adults in an era of demographic change.

作者信息

Doherty T Mark, Connolly Mark P, Del Giudice Giuseppe, Flamaing Johan, Goronzy Jorg J, Grubeck-Loebenstein Beatrix, Lambert Paul-Henri, Maggi Stefania, McElhaney Janet E, Nagai Hideaki, Schaffner William, Schmidt-Ott Ruprecht, Walsh Edward, Di Pasquale Alberta

机构信息

GSK, Wavre, Belgium.

Global Market Access Solutions, St-Prex, Switzerland.

出版信息

Eur Geriatr Med. 2018;9(3):289-300. doi: 10.1007/s41999-018-0040-8. Epub 2018 Mar 19.

Abstract

OBJECTIVES

Populations are aging worldwide. This paper summarizes some of the challenges and opportunities due to the increasing burden of infectious diseases in an aging population.

RESULTS

Older adults typically suffer elevated morbidity from infectious disease, leading to increased demand for healthcare resources and higher healthcare costs. Preventive medicine, including vaccination can potentially play a major role in preserving the health and independence of older adults. However, this potential of widespread vaccination is rarely realized. Here, we give a brief overview of the problem, discuss concrete obstacles and the potential for expanded vaccination programs to promote healthy aging.

CONCLUSION

The increasing healthcare burden of infectious diseases expected in aging populations could, to a large extent, be reduced by achieving higher vaccination coverage among older adults. Vaccination can thus contribute to healthy aging, alongside healthy diet and physical exercise. The available evidence indicates that dedicated programs can achieve substantial improvements in vaccination coverage among older adults, but more research is required to assess the generalizability of the results achieved by specific interventions (see Additional file 1).

摘要

目标

全球人口正在老龄化。本文总结了老龄化人口中传染病负担增加所带来的一些挑战和机遇。

结果

老年人通常因传染病而发病率升高,导致对医疗资源的需求增加和医疗成本上升。包括疫苗接种在内的预防医学可能在维护老年人的健康和独立性方面发挥重要作用。然而,广泛接种疫苗的这一潜力很少得到实现。在此,我们简要概述这一问题,讨论具体障碍以及扩大疫苗接种计划以促进健康老龄化的潜力。

结论

通过提高老年人的疫苗接种覆盖率,有望在很大程度上减轻老龄化人口中预期的传染病日益增加的医疗负担。因此,疫苗接种与健康饮食和体育锻炼一样,可有助于健康老龄化。现有证据表明,专门的计划可大幅提高老年人的疫苗接种覆盖率,但需要更多研究来评估特定干预措施所取得结果的可推广性(见补充文件1)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d812/5972173/7438ee4d314a/41999_2018_40_Fig1_HTML.jpg

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