Burruni Rodolfo, Lhermitte Benoit, Cerantola Yannick, Tawadros Thomas, Meuwly Jean-Yves, Berthold Dominik, Jichlinski Patrice, Valerio Massimo
Department of Urology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Department of Pathology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Can Urol Assoc J. 2016 Jan-Feb;10(1-2):E28-33. doi: 10.5489/cuaj.3417. Epub 2016 Jan 14.
Renal biopsy is being increasingly proposed as a diagnostic tool to characterize small renal masses (SRM). Indeed, the wide adoption of imaging in the diagnostic workup of many diseases had led to a substantial increased incidence of SRM (diameter ≤4 cm). While modern ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI) techniques have high sensitivity for detecting SRM, none is able to accurately and reliably characterize them in terms of histological features. This is currently of key importance in guiding clinical decision-making in some situations, and in these cases renal biopsy should be considered. In this review, we aim to summarize the technique, diagnostic performance, and predicting factors of nondiagnostic biopsy, as well as the future perspectives.
肾活检越来越多地被用作一种诊断工具,以对小肾肿块(SRM)进行特征描述。事实上,许多疾病的诊断检查中广泛采用影像学检查,导致SRM(直径≤4厘米)的发病率大幅上升。虽然现代超声、计算机断层扫描(CT)和磁共振成像(MRI)技术对检测SRM具有高敏感性,但就组织学特征而言,没有一种技术能够准确可靠地对它们进行特征描述。这在某些情况下指导临床决策方面目前至关重要,在这些情况下应考虑进行肾活检。在本综述中,我们旨在总结该技术、诊断性能、非诊断性活检的预测因素以及未来展望。