Hall Allan, White Mark A J, Gallo Pasquale
Institute of Neurological Sciences, Queen Elizabeth University Hospital, Glasgow, United Kingdom.
Department of Clinical Neurosciences, Western General Hospital, Edinburgh, United Kingdom.
Int J Surg Case Rep. 2016;20:138-41. doi: 10.1016/j.ijscr.2016.01.025. Epub 2016 Jan 25.
We present an unusual case where a large intra-cerebral abscess with severe complications was treated successfully with medical management alone in a patient with Eisenmenger syndrome.
A 40 year old patient with Eisenmenger syndrome presented with a seven day history of headache, neck pain and intermittent vomiting and fever. The only neurological examination finding was blurred vision. MRI revealed a large left occipital lobe abscess, which subsequently ruptured into the lateral ventricle with associated ventriculitis and hydrocephalus. This complicated abscess was successfully treated with intravenous antibiotics alone, with complete resolution of the abscess and hydrocephalus on MRI at 13 months post-diagnosis.
Patients with congenital cyanotic heart conditions, like Eisenmenger syndrome, are at increased risk of developing intra-cerebral abscesses. Effectively managing large abscesses with associated intra-ventricular rupture and hydrocephalus in these patients without any form of surgical intervention, including aspiration, is extremely rare.
Patients with congenital cyanotic heart disease who develop large intra-cerebral abscesses with severe complications, which would normally warrant surgical intervention, have the potential to be successfully treated with antibiotics alone with excellent outcome.
我们报告了一例罕见病例,一名患有艾森曼格综合征的患者,其巨大的脑内脓肿伴有严重并发症,仅通过药物治疗就成功治愈。
一名40岁的艾森曼格综合征患者,有7天的头痛、颈部疼痛、间歇性呕吐和发热病史。唯一的神经系统检查发现是视力模糊。MRI显示左枕叶有一个巨大脓肿,随后脓肿破裂进入侧脑室,伴有脑室炎和脑积水。这个复杂的脓肿仅通过静脉注射抗生素就成功治愈,诊断后13个月时MRI显示脓肿和脑积水完全消退。
患有先天性青紫型心脏病的患者,如艾森曼格综合征,发生脑内脓肿的风险增加。在这些患者中,在没有任何形式的手术干预(包括抽吸)的情况下,有效治疗伴有脑室破裂和脑积水的巨大脓肿极为罕见。
患有先天性青紫型心脏病且发生巨大脑内脓肿并伴有严重并发症(通常需要手术干预)的患者,有可能仅通过抗生素成功治疗并取得良好效果。