• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

艾森曼格综合征患者的脑内脓肿:一例罕见病例。

An intra-cerebral abscess in a patient with Eisenmenger syndrome: An unusual case.

作者信息

Hall Allan, White Mark A J, Gallo Pasquale

机构信息

Institute of Neurological Sciences, Queen Elizabeth University Hospital, Glasgow, United Kingdom.

Department of Clinical Neurosciences, Western General Hospital, Edinburgh, United Kingdom.

出版信息

Int J Surg Case Rep. 2016;20:138-41. doi: 10.1016/j.ijscr.2016.01.025. Epub 2016 Jan 25.

DOI:10.1016/j.ijscr.2016.01.025
PMID:26859871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4818319/
Abstract

INTRODUCTION

We present an unusual case where a large intra-cerebral abscess with severe complications was treated successfully with medical management alone in a patient with Eisenmenger syndrome.

PRESENTATION OF CASE

A 40 year old patient with Eisenmenger syndrome presented with a seven day history of headache, neck pain and intermittent vomiting and fever. The only neurological examination finding was blurred vision. MRI revealed a large left occipital lobe abscess, which subsequently ruptured into the lateral ventricle with associated ventriculitis and hydrocephalus. This complicated abscess was successfully treated with intravenous antibiotics alone, with complete resolution of the abscess and hydrocephalus on MRI at 13 months post-diagnosis.

DISCUSSION

Patients with congenital cyanotic heart conditions, like Eisenmenger syndrome, are at increased risk of developing intra-cerebral abscesses. Effectively managing large abscesses with associated intra-ventricular rupture and hydrocephalus in these patients without any form of surgical intervention, including aspiration, is extremely rare.

CONCLUSION

Patients with congenital cyanotic heart disease who develop large intra-cerebral abscesses with severe complications, which would normally warrant surgical intervention, have the potential to be successfully treated with antibiotics alone with excellent outcome.

摘要

引言

我们报告了一例罕见病例,一名患有艾森曼格综合征的患者,其巨大的脑内脓肿伴有严重并发症,仅通过药物治疗就成功治愈。

病例介绍

一名40岁的艾森曼格综合征患者,有7天的头痛、颈部疼痛、间歇性呕吐和发热病史。唯一的神经系统检查发现是视力模糊。MRI显示左枕叶有一个巨大脓肿,随后脓肿破裂进入侧脑室,伴有脑室炎和脑积水。这个复杂的脓肿仅通过静脉注射抗生素就成功治愈,诊断后13个月时MRI显示脓肿和脑积水完全消退。

讨论

患有先天性青紫型心脏病的患者,如艾森曼格综合征,发生脑内脓肿的风险增加。在这些患者中,在没有任何形式的手术干预(包括抽吸)的情况下,有效治疗伴有脑室破裂和脑积水的巨大脓肿极为罕见。

结论

患有先天性青紫型心脏病且发生巨大脑内脓肿并伴有严重并发症(通常需要手术干预)的患者,有可能仅通过抗生素成功治疗并取得良好效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b87/4818319/73cdb951934a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b87/4818319/db2d59893d25/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b87/4818319/73cdb951934a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b87/4818319/db2d59893d25/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b87/4818319/73cdb951934a/gr2.jpg

相似文献

1
An intra-cerebral abscess in a patient with Eisenmenger syndrome: An unusual case.艾森曼格综合征患者的脑内脓肿:一例罕见病例。
Int J Surg Case Rep. 2016;20:138-41. doi: 10.1016/j.ijscr.2016.01.025. Epub 2016 Jan 25.
2
Brain abscess associated with ventricular septal defect and Eisenmenger syndrome: A case report.脑脓肿合并室间隔缺损及艾森曼格综合征:一例报告
Int J Surg Case Rep. 2021 Apr;81:105799. doi: 10.1016/j.ijscr.2021.105799. Epub 2021 Mar 19.
3
Current treatment of brain abscess in patients with congenital cyanotic heart disease.先天性青紫型心脏病患者脑脓肿的当前治疗方法。
Neurosurgery. 1997 Dec;41(6):1270-8; discussion 1278-9. doi: 10.1097/00006123-199712000-00006.
4
Cerebral abscess as a neurosurgical emergency in Eisenmenger syndrome: illustrative case.艾森曼格综合征中的脑脓肿作为一种神经外科急症:病例说明
J Neurosurg Case Lessons. 2022 Aug 1;4(5). doi: 10.3171/CASE2252.
5
Cerebral Abscess in Young Adult with Hypoplastic Left Heart Syndrome.患有左心发育不全综合征的年轻成年人的脑脓肿
World Neurosurg. 2018 Aug;116:201-204. doi: 10.1016/j.wneu.2018.05.097. Epub 2018 May 23.
6
[Brain abscess ruptured into the lateral ventricle: the usefulness of treatment by intraventricular irrigation with antibiotics. A case report].[脑脓肿破入侧脑室:抗生素脑室内冲洗治疗的有效性。病例报告]
No Shinkei Geka. 1994 Jul;22(7):689-93.
7
Primary Intraventricular Brain Abscess Resulting in Isolated Dilation of the Inferior Horn and Unilateral Hydrocephalus.原发性脑室内脑脓肿导致下角孤立性扩张和单侧脑积水。
Case Rep Neurol. 2015 Jul 23;7(2):156-61. doi: 10.1159/000437255. eCollection 2015 May-Aug.
8
Unexpected Origins: A Case Report of Escherichia coli-Linked Cerebral Abscess in an Adult.意外起源:一例成人大肠杆菌相关性脑脓肿病例报告
Cureus. 2024 Sep 3;16(9):e68592. doi: 10.7759/cureus.68592. eCollection 2024 Sep.
9
Actinomyces meyeri-induced brain abscess in pregnancy: a case report.梅耶放线菌致妊娠脑脓肿:病例报告。
BMC Neurol. 2023 Nov 11;23(1):401. doi: 10.1186/s12883-023-03453-7.
10
[Pathogenesis and methods of treatment of otogenic brain abscess].[耳源性脑脓肿的发病机制及治疗方法]
Med Pregl. 1998 Jan-Feb;51(1-2):51-5.

引用本文的文献

1
Cerebral abscess as a neurosurgical emergency in Eisenmenger syndrome: illustrative case.艾森曼格综合征中的脑脓肿作为一种神经外科急症:病例说明
J Neurosurg Case Lessons. 2022 Aug 1;4(5). doi: 10.3171/CASE2252.
2
Giant Actinomyces brain abscess in an immunocompetent child: A management strategy.免疫功能正常儿童的巨大放线菌脑脓肿:一种管理策略。
Surg Neurol Int. 2021 Jul 6;12:325. doi: 10.25259/SNI_164_2021. eCollection 2021.

本文引用的文献

1
Brain abscess: Current management.脑脓肿:当前的治疗方法。
J Neurosci Rural Pract. 2013 Aug;4(Suppl 1):S67-81. doi: 10.4103/0976-3147.116472.
2
Brain abscess due to Propionibacterium propionicum in Eisenmenger syndrome.
Med J Aust. 2012 May 7;196(8):525-6. doi: 10.5694/mja11.10768.
3
Consensus document on controversial issues for the treatment of infections of the central nervous system: bacterial brain abscesses.关于中枢神经系统感染治疗的争议问题共识文件:细菌性脑脓肿。
Int J Infect Dis. 2010 Oct;14 Suppl 4:S79-92. doi: 10.1016/j.ijid.2010.05.010. Epub 2010 Sep 16.
4
Management of brain abscess: an overview.脑脓肿的管理:概述
Neurosurg Focus. 2008;24(6):E3. doi: 10.3171/FOC/2008/24/6/E3.
5
Prodromal signs and clinical factors influencing outcome in patients with intraventricular rupture of purulent brain abscess.前驱症状及临床因素对化脓性脑脓肿脑室破裂患者预后的影响
Neurosurgery. 2001 Feb;48(2):310-6; discussion 316-7.
6
Current treatment of brain abscess in patients with congenital cyanotic heart disease.先天性青紫型心脏病患者脑脓肿的当前治疗方法。
Neurosurgery. 1997 Dec;41(6):1270-8; discussion 1278-9. doi: 10.1097/00006123-199712000-00006.
7
Brain abscess.脑脓肿
Clin Infect Dis. 1997 Oct;25(4):763-79; quiz 780-1. doi: 10.1086/515541.