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[脑脓肿破入侧脑室:抗生素脑室内冲洗治疗的有效性。病例报告]

[Brain abscess ruptured into the lateral ventricle: the usefulness of treatment by intraventricular irrigation with antibiotics. A case report].

作者信息

Sato M, Oikawa T, Sasaki T, Kodama N

机构信息

Department of Neurosurgery, Fukushima Medical School, Japan.

出版信息

No Shinkei Geka. 1994 Jul;22(7):689-93.

PMID:8078604
Abstract

A case is reported of a brain abscess, which ruptured into the lateral ventricle and was treated using intraventricular irrigation with antibiotics. A 37-year-old man was suffering from a headache and high fever. Precontrast CT scan revealed a heterogeneous low density area in the left temporal lobe, and postcontrast CT scan showed a multilobular ring-like enhanced mass. Diagnosed as a brain abscess, intravenous administration of antibiotics was performed. On the sixth day the patient suddenly became drowsy. Postcontrast CT scan revealed an enhanced effect in the left lateral ventricular wall. Drowsiness was attributed to increased intracranial pressure and severe ventriculitis. Bilateral continuous ventricular drainage via the anterior horn of the lateral ventricle was performed. The drainage fluid from the left lateral ventricle was just like pus. Intraventricular irrigation with antibiotics between the bilateral anterior horns of the lateral ventricle, was performed in order to save the patient. The infusion fluid, Lactate Ringer's solution containing Cefazolin sodium, was infused into the right ventricle and CSF-like pus was drained from the left ventricle. The CSF reading gradually improved, and on the 14th day postoperatively irrigation was terminated. The postoperative course was uneventful. The diagnosis, treatment, and prognosis of patients with brain abscesses have improved dramatically as a result of more reliable methods of identifying infecting organisms, more effective antibiotic regimens, the development of microsurgical techniques and CT scan. However, despite these advances, the prognosis for brain abscess ruptured into the ventricle is usually very pessimistic.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本文报告一例脑脓肿破入侧脑室并采用抗生素脑室内冲洗治疗的病例。一名37岁男性,出现头痛和高热症状。增强扫描前CT显示左颞叶有一不均匀低密度区,增强扫描后CT显示为多叶环状强化肿块。诊断为脑脓肿后,进行了静脉抗生素治疗。第六天患者突然嗜睡。增强扫描后CT显示左侧脑室壁有强化效应。嗜睡归因于颅内压升高和严重的脑室炎。通过侧脑室前角进行双侧持续脑室引流。左侧脑室引流液呈脓性。为挽救患者生命,在双侧脑室前角之间进行了抗生素脑室内冲洗。将含有头孢唑林钠的乳酸林格液注入右心室,从左心室引流类似脑脊液的脓液。脑脊液指标逐渐改善,术后第14天停止冲洗。术后病程平稳。由于识别感染病原体的方法更可靠、抗生素治疗方案更有效、显微外科技术的发展以及CT扫描技术的应用,脑脓肿患者的诊断、治疗和预后有了显著改善。然而,尽管有这些进展,脑脓肿破入脑室的预后通常非常悲观。(摘要截短至250字)

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Successful neuroendoscopic treatment of intraventricular brain abscess rupture.
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