Gorshkova G I, Bogomolova T S, Kornev N R, Pakhomova E N, Labunets I A
Zh Mikrobiol Epidemiol Immunobiol. 1989 Sep(9):7-11.
The biotyping of 284 C. albicans strains has been carried out in accordance with the system of three tests, proposed by F.C. Odds and A. B. Abbott. The reliability of the epidemiological conclusions made as the result of this work has been analyzed. The independence of the signs of C. albicans used in biotyping and the asymmetrical character of the test for its sensitivity to 5-fluorocytosine have been shown. The change of this test for a more symmetrical one is proposed. The study has shown that in the process of prolonged storage with periodic subculturing the proportion of C. albicans strains resistant to pH 1.40 and possessing proteolytic activity is decreased. The distribution of different biotypes among C. albicans strains isolated from candidiasis patients and from carriers has proved to be the same.
按照F.C. Odds和A.B. Abbott提出的三项试验系统，对284株白色念珠菌进行了生物分型。分析了这项工作所得出的流行病学结论的可靠性。已表明白色念珠菌生物分型中所使用特征的独立性以及其对5-氟胞嘧啶敏感性试验的不对称性。建议将该试验改为更具对称性的试验。研究表明，在定期传代的长期保存过程中，对pH 1.40有抗性且具有蛋白水解活性的白色念珠菌菌株比例会降低。从念珠菌病患者和携带者中分离出的白色念珠菌菌株中不同生物型的分布已证明是相同的。
