Sultana Shabiya, Zulkifle Mohd, Ansari Abdul Haseeb
Department of Tahaffuzi wa Samaji Tib, National Institute of Unani Medicine, Bengaluru, Karnataka, India.
Department of Kulliyat, National Institute of Unani Medicine, Bengaluru, Karnataka, India.
Anc Sci Life. 2015 Oct-Dec;35(2):124-8. doi: 10.4103/0257-7941.171668.
Buthūr-i-Labaniyya (Acne vulgaris) is affecting up to 80% of adolescents and many adults at different stages of life. It is one of the commonest skin disorders which appears on cheeks and nose as white eruptions that seems like solidified milk drops. These eruptions are treated by drugs having properties of tajfīf wa taḥlīl (desiccant and resolving), as mentioned by Ibne Sina. Daood Antaki in his book Tazkira Oolulalbab recommends the local application of a paste of Shonīz (nigella sativa), Naushādar (ammonium chloride) and Būra Armani mixed with Sirka (vinegar) for effective treatment of Acne vulgaris.
The study was observational self comparison before and after treatment, conducted in the OPD of the hospital which is part of the National Institute of Unani Medicine, Bangalore. The duration of study was one year. 40 Female patients with combination of comedones, papules, pustules and nodules were recruited for this purpose. The test drug, Shonīz, Būra Armani, Naushadar powder, mixed with sirka were applied locally for one month with taqlīl-i-ghidhā tadābīr (low calorie index diet). All subjects were assessed on the basis of changes in subjective and objective parameters.
The response of test drugs was statistically highly significant (P < 0.01) by using ANOVA repeated measure test, there was also relief in subjective parameters. Subjects reported a reduction of 82.6%, 80.9%, 66.6% in tenderness, itching and irritation respectively.
The present study reveals that the test drug formulation is safe and effective in treating Acne vulgaris if used along with low calorie index diet. No side effects of drugs were reported, therefore the trial formulation can be recommended to manage Acne vulgaris of mild to severe degree as a therapy.
寻常痤疮影响着高达80%的青少年以及许多处于不同人生阶段的成年人。它是最常见的皮肤疾病之一，表现为脸颊和鼻子上出现白色皮疹，类似凝固的奶滴。如伊本·西那所述，这些皮疹通过具有干燥和消散特性的药物进行治疗。达乌德·安塔基在其著作《Tazkira Oolulalbab》中推荐局部应用由黑种草、氯化铵和硼酸与醋混合而成的糊剂来有效治疗寻常痤疮。
本研究为治疗前后的观察性自身对照研究，在班加罗尔国家尤纳尼医学研究所所属医院的门诊进行。研究持续时间为一年。为此招募了40名患有粉刺、丘疹、脓疱和结节的女性患者。将受试药物黑种草、硼酸、氯化铵粉末与醋混合后局部应用一个月，并配合低热量指数饮食。所有受试者根据主观和客观参数的变化进行评估。
使用重复测量方差分析，受试药物的反应在统计学上具有高度显著性（P < 0.01），主观参数也有所缓解。受试者报告压痛、瘙痒和刺激分别减轻了82.6%、80.9%和66.6%。
本研究表明，受试药物配方与低热量指数饮食一起使用时，在治疗寻常痤疮方面是安全有效的。未报告药物的副作用，因此该试验配方可作为一种疗法推荐用于治疗轻至重度寻常痤疮。
