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使用自体和异体培养上皮(新鲜的或冷冻保存的)治疗烧伤的多中心经验。

Multicentre experience in the treatment of burns with autologous and allogenic cultured epithelium, fresh or preserved in a frozen state.

作者信息

De Luca M, Albanese E, Bondanza S, Megna M, Ugozzoli L, Molina F, Cancedda R, Santi P L, Bormioli M, Stella M

机构信息

Laboratory of Cell Differentiation, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.

出版信息

Burns. 1989 Oct;15(5):303-9. doi: 10.1016/0305-4179(89)90007-7.

DOI:10.1016/0305-4179(89)90007-7
PMID:2686683
Abstract

This report describes the clinical results obtained from a multicentre experience of the use of autologous and allogenic cultured human epidermal cells in the treatment of partial and full skin thickness burns. A laboratory has been organized to supply cultured epithelium to Burns Units in different cities. From May 1986 to December 1988, 58 patients with an age range of 1 to 59 years, and with burns covering between 7 and 95 per cent of the body surface area, have been treated. Graftable cultured epithelium can be frozen and remain viable if stored in a skin bank. Such grafts were used successfully to treat patients with partial and full skin thickness wounds.

摘要

本报告描述了在多中心使用自体和异体培养人表皮细胞治疗部分和全层皮肤烧伤的临床结果。已组建一个实验室,为不同城市的烧伤科提供培养的上皮细胞。从1986年5月至1988年12月,共治疗了58例患者,年龄在1至59岁之间,烧伤面积占体表面积的7%至95%。可移植的培养上皮细胞可以冷冻保存,若储存在皮肤库中仍可存活。此类移植物已成功用于治疗部分和全层皮肤伤口的患者。

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