Kahan A, Amor B, Menkes C J
Clinique de Rhumatologie et Service de Rhumatologie A, Hôpital Cochin, Paris, France.
Biomed Pharmacother. 1989;43(6):401-3. doi: 10.1016/0753-3322(89)90236-9.
Evanescent arthralgias and myalgias are common early symptoms of Lyme disease. Transient, intermittent episodes of monoarticular, oligoarticular, or sometimes migratory polyarticular arthritis, lasting weeks to months, with disease-free intervals, are frequently observed in untreated patients with erythema chronicum migrans. A minority of patients develop chronic joint involvement, most commonly affecting the knee. Antibiotic therapy given during erythema chronicum migrans is often protective with regard to late joint manifestations. In chronic Lyme arthritis, however, the response to antibiotics is variable.
短暂性关节痛和肌痛是莱姆病常见的早期症状。在未经治疗的慢性游走性红斑患者中，常可见到单关节、少关节或有时为游走性多关节关节炎的短暂、间歇性发作，持续数周数月，有疾病缓解期。少数患者会出现慢性关节受累，最常见的是膝关节。在慢性游走性红斑阶段给予抗生素治疗通常对预防晚期关节表现有保护作用。然而，在慢性莱姆关节炎中，对抗生素的反应各不相同。
