Bitar Imad, Lally Edward V
Roger Williams Medical Center, USA.
Med Health R I. 2008 Jul;91(7):213-5.
Musculoskeletal symptoms in Lyme disease are very common at all stages of the disease. Lyme arthritis, whether intermittent or chronic, is a hallmark of late Lyme disease. This may cause severe joint pain and swelling especially confined to one or a few joints, most notably the knee. Antibiotic therapy is very effective in treating Lyme arthritis in the majority of cases. However, a small proportion of individuals will develop persistent chronic arthritis which is likely mediated through immunologic mechanisms. In these patients treatment strategies should include anti-inflammatory medications and possibly immunosuppressive treatments. Arthroscopic synovectomy ma ybe very helpful in some of these patients. Post Lyme disease syndrome and Lyme myositis are two other sequelae that are associated with Lyme disease.
莱姆病的肌肉骨骼症状在疾病的各个阶段都非常常见。莱姆关节炎，无论是间歇性还是慢性的，都是晚期莱姆病的一个标志。这可能会导致严重的关节疼痛和肿胀，尤其是局限于一个或几个关节，最常见的是膝盖。在大多数情况下，抗生素治疗对莱姆关节炎非常有效。然而，一小部分人会发展为持续性慢性关节炎，这可能是由免疫机制介导的。对于这些患者，治疗策略应包括使用抗炎药物，可能还需要免疫抑制治疗。关节镜下滑膜切除术可能对其中一些患者非常有帮助。莱姆病后综合征和莱姆肌炎是与莱姆病相关的另外两种后遗症。
