Gilbert Laura J, Li Ping, Murray Clinton K, Yun Heather C, Aggarwal Deepak, Weintrob Amy C, Tribble David R
Walter Reed National Military Medical Center, Bethesda, MD, USA.
Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD USA.
Diagn Microbiol Infect Dis. 2016 Apr;84(4):358-60. doi: 10.1016/j.diagmicrobio.2015.12.014. Epub 2015 Dec 23.
Prior studies have demonstrated high rates of colonization and infection with multidrug-resistant gram-negative bacilli (MDR-GNB) in injured military personnel. Our analysis shows that injuries inflicted during peak combat periods, massive blood transfusion requirement, and posttrauma cefazolin prophylaxis (additive effect with fluoroquinolones) were risk factors for MDR-GNB colonization.
先前的研究表明,受伤军事人员中多重耐药革兰氏阴性杆菌(MDR-GNB)的定植和感染率很高。我们的分析表明,在战斗高峰期受伤、大量输血需求以及创伤后头孢唑林预防(与氟喹诺酮类药物有相加作用)是MDR-GNB定植的危险因素。