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人工耳蜗植入中健康效用工具之间的一致性。

Agreement between health utility instruments in cochlear implantation.

作者信息

Ramakers G G J, Smulders Y E, van Zon A, Kraaijenga V J C, Stegeman I, Van Zanten G A, Grolman W

机构信息

Department of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands.

出版信息

Clin Otolaryngol. 2016 Dec;41(6):737-743. doi: 10.1111/coa.12626. Epub 2016 Feb 12.

Abstract

OBJECTIVES

The objectives of our study were threefold: to compare health utility scores measured with different health utility instruments in adult patients with bilateral deafness, to compare the change in health utility scores after unilateral or bilateral cochlear implantation using the different health utility instruments and to assess which health utility instrument would be the most appropriate for future studies on cochlear implantation.

DESIGN

A prospective study.

SETTING

The data for this article were collected as part of a multicentre randomised controlled trial in the Netherlands on the benefits of simultaneous bilateral cochlear implantation compared to unilateral cochlear implantation.

PARTICIPANTS

The study included 38 adult patients with severe to profound bilateral post-lingual sensorineural hearing loss.

MAIN OUTCOME MEASURES

Participants completed various quality of life questionnaires (the EuroQol five-dimensional questionnaire (EQ-5D), the Health Utilities Index mark 3 (HUI3), a visual analogue scale (VAS) for general quality of life and a VAS for hearing) preoperatively, and one and two years postoperatively. The general health utility instruments (EQ-5D, HUI3 and VAS general) were compared.

RESULTS

The EQ-5D, HUI3 and VAS general utility scores differed significantly. The intraclass correlation coefficients showed poor to no agreement between these instruments. A gain in health utility after cochlear implantation was found with the HUI3 and VAS general. The highest gain in health utility was found with the HUI3.

CONCLUSIONS

A health utility score depends on the health utility instrument that is used in a specific patient population. We recommend using the HUI3 in future studies on cochlear implantation.

摘要

目的

我们研究的目的有三个:比较成年双侧耳聋患者使用不同健康效用工具测得的健康效用得分;比较使用不同健康效用工具在单侧或双侧人工耳蜗植入术后健康效用得分的变化;评估哪种健康效用工具最适合未来人工耳蜗植入的研究。

设计

一项前瞻性研究。

背景

本文的数据是作为荷兰一项关于同期双侧人工耳蜗植入与单侧人工耳蜗植入效益的多中心随机对照试验的一部分收集的。

参与者

该研究纳入了38例患有重度至极重度双侧语后感觉神经性听力损失的成年患者。

主要观察指标

参与者在术前、术后1年和2年完成了各种生活质量问卷(欧洲五维健康量表(EQ-5D)、健康效用指数第3版(HUI3)、一般生活质量视觉模拟量表(VAS)和听力VAS)。对一般健康效用工具(EQ-5D、HUI3和VAS一般量表)进行了比较。

结果

EQ-5D、HUI3和VAS一般效用得分差异显著。组内相关系数显示这些工具之间的一致性较差或无一致性。使用HUI3和VAS一般量表发现人工耳蜗植入后健康效用有所提高。使用HUI3发现健康效用提高最多。

结论

健康效用得分取决于在特定患者群体中使用的健康效用工具。我们建议在未来人工耳蜗植入的研究中使用HUI3。

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