Yuan H A, Zhu F H, Liu W J, Li Q J, Yang B L
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1989;7(3):184-6.
215 patients of vivax malaria were treated with chloroquine phosphate alone at the dose of 1.5g for three days from April 1986 to October 1987 in Cili County in the northwest part of Hunan Province. Among them, 58 cases relapsed, the relapse rate being 27.0%. In patients admitted in April and May, as judged from the interval between treatment and the first relapse, the latent period was short, between 60.8d and 63.5d. On the contrary, when chloroquine treatment was given in August and September, the latent period in all the patients was long, between 292.4d and 297.5d. It is very interesting to note that in patients treated in June and July, both long and short latent periods occurred. 72.7% of the patients treated in June had short latent period (63.7d), while 75.0% of the patients treated in July had long latent period (285.4d).
1986年4月至1987年10月期间，湖南省西北部慈利县的215例间日疟患者仅接受磷酸氯喹治疗，剂量为1.5克，疗程三天。其中58例复发，复发率为27.0%。4月和5月入院的患者，从治疗到首次复发的间隔时间判断，潜伏期较短，在60.8天至63.5天之间。相反，8月和9月进行氯喹治疗时，所有患者的潜伏期都很长，在292.4天至297.5天之间。值得注意的是，6月和7月接受治疗的患者中，出现了潜伏期长短不一的情况。6月接受治疗的患者中，72.7%的患者潜伏期较短（63.7天），而7月接受治疗的患者中，75.0%的患者潜伏期较长（285.4天）。
