Ali Abdullatif D, Mehrass Amat Al-Khaleq O, Al-Adhroey Abdulelah H, Al-Shammakh Abdulqawi A, Amran Adel A
Department of Biochemistry, Thamar University, Dhamar, Yemen.
Department of Gynecology and Obstetrics, Thamar University, Dhamar, Yemen.
Int J Womens Health. 2016 Jan 25;8:35-41. doi: 10.2147/IJWH.S97502. eCollection 2016.
Gestational diabetes mellitus (GDM) continues to be a significant health disorder triggering harmful complications in pregnant women and fetuses. Our knowledge of GDM epidemiology in Yemen is largely based on very limited data. The aim of this study was, therefore, to determine the prevalence and risk factors of GDM among pregnant women in Dhamar governorate, Yemen.
A total of 311 subjects were randomly selected for this cross sectional survey. Health history data and blood samples were collected using a pretested questionnaire. To determine the prevalence of GDM, the fasting and random blood glucose techniques were applied according to the recommendations of the American Diabetes Association, using alternative methods that are more convenient to the targeted population. Poisson's regression model incorporating robust sandwich variance was utilized to assess the association of potential risk factors in developing GDM.
The prevalence of GDM was found to be 5.1% among the study population. Multivariate analysis confirmed age ≥30 years, previous GDM, family history of diabetes, and history of polycystic ovary syndrome as independent risk factors for GDM prevalence. However, body mass index ≥30 kg/m(2) and previous macrosomic baby were found to be dependent risk factors.
This study reports new epidemiological information about the prevalence and risk factors of GDM in Yemen. Introduction of proper maternal and neonatal medical care and health education are important in order to save the mother and the baby.
妊娠期糖尿病(GDM)仍然是一种严重的健康疾病,会引发孕妇和胎儿的有害并发症。我们对也门GDM流行病学的了解很大程度上基于非常有限的数据。因此,本研究的目的是确定也门达马尔省孕妇中GDM的患病率和危险因素。
本横断面调查共随机选取311名受试者。使用预先测试的问卷收集健康史数据和血样。为了确定GDM的患病率,根据美国糖尿病协会的建议,采用空腹和随机血糖技术,并使用对目标人群更方便的替代方法。采用纳入稳健三明治方差的泊松回归模型评估发生GDM的潜在危险因素之间的关联。
研究人群中GDM的患病率为5.1%。多变量分析证实,年龄≥30岁、既往患GDM、糖尿病家族史和多囊卵巢综合征病史是GDM患病率的独立危险因素。然而,体重指数≥30kg/m²和既往有巨大儿病史是相关危险因素。
本研究报告了也门GDM患病率和危险因素的新流行病学信息。引入适当的母婴医疗护理和健康教育对于拯救母婴至关重要。