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伴有多发型淋巴瘤性息肉病和肠套叠的套细胞淋巴瘤:一例报告

Mantle cell lymphoma with multiple lymphomatous polyposis and intussusception: A case report.

作者信息

Lee Jae Min, Kim Eun Sun, Choi Hyuk Soon, Keum Bora, Jeen Yoon Tae, Lee Hong Sik, Chun Hoon Jai, Kim Chang Duck, Ryu Ho Sang, Kim Insun

机构信息

Department of Internal Medicine, Division of Gastroenterology and Hepatology, Korea University College of Medicine, Seoul 136-705, Republic of Korea.

Department of Pathology, Korea University Anam Hospital, Seoul 136-705, Republic of Korea.

出版信息

Oncol Lett. 2016 Jan;11(1):654-656. doi: 10.3892/ol.2015.3954. Epub 2015 Nov 23.

Abstract

Mantle cell lymphoma (MCL) is a rare malignant lymphoma of the gastrointestinal (GI) tract that may present as multiple lymphomatous polyposis (MLP); however, MLP with intussusception is rarely reported in MCL. In the present study, a 54-year-old male patient was diagnosed with MCL, presenting with numerous polypoid lesions of the complete GI tract combined with ileocecal intussusception. Right hemicolectomy was performed in order to prevent complicated intussusception and for tumor debulking. In addition, 6 cycles of chemotherapy were performed with the rituximab plus hyper-CVAD regimen. Subsequent to the planned chemotherapy cycles, follow-up examination demonstrated a complete response and the remission lasted for 3 years until the present time.

摘要

套细胞淋巴瘤(MCL)是一种罕见的胃肠道恶性淋巴瘤,可表现为多发性淋巴瘤性息肉病(MLP);然而,MCL中伴有肠套叠的MLP鲜有报道。在本研究中,一名54岁男性患者被诊断为MCL,表现为全胃肠道多发息肉样病变并伴有回盲部肠套叠。为预防复杂肠套叠及肿瘤减瘤,行右半结肠切除术。此外,采用利妥昔单抗加hyper-CVAD方案进行了6个周期的化疗。在计划的化疗周期之后,随访检查显示完全缓解,缓解持续至今已3年。

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Treatment of older patients with mantle-cell lymphoma.治疗老年套细胞淋巴瘤患者。
N Engl J Med. 2012 Aug 9;367(6):520-31. doi: 10.1056/NEJMoa1200920.
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Mantle cell lymphoma as a rare cause of intussusception: a report of 2 cases.套细胞淋巴瘤作为肠套叠的罕见病因:2 例报告。
Ann Diagn Pathol. 2009 Dec;13(6):398-401. doi: 10.1016/j.anndiagpath.2009.03.003. Epub 2009 Apr 22.
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Improvement of overall survival in advanced stage mantle cell lymphoma.晚期套细胞淋巴瘤总生存期的改善
J Clin Oncol. 2009 Feb 1;27(4):511-8. doi: 10.1200/JCO.2008.16.8435. Epub 2008 Dec 15.
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Therapy of mantle cell lymphoma: current standards and future strategies.套细胞淋巴瘤的治疗:当前标准与未来策略
Hematol Oncol Clin North Am. 2008 Oct;22(5):953-63, ix. doi: 10.1016/j.hoc.2008.07.001.

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