Rufli T
Department of Dermatology, University Hospital, Basel, Switzerland.
Dermatologica. 1989;179(3):113-7. doi: 10.1159/000248335.
Treponema pallidum and HIV are both sexually transmitted agents of infectious diseases with epidemiological similarities. Ulcerous genital diseases such as primary syphilis facilitate transmission of HIV. An increasing number of case reports gives evidence that in HIV-infected patients secondary syphilis runs a more severe course and may present as syphilis maligna and that neurological complications of secondary and tertiary syphilis seem to occur more frequently and at an earlier stage. The clinical evaluation, interpretation of serology and choice of treatment schedules must take these considerations into account.
梅毒螺旋体和人类免疫缺陷病毒（HIV）都是具有流行病学相似性的性传播传染病病原体。原发性梅毒等溃疡性生殖器疾病会促进HIV的传播。越来越多的病例报告表明，在HIV感染患者中，二期梅毒病程更为严重，可能表现为恶性梅毒，并且二期和三期梅毒的神经并发症似乎更频繁且更早出现。临床评估、血清学解读和治疗方案的选择都必须考虑到这些因素。
