SDM College (Autonomous), Ujire, Belthangadi Taluk, Dakshina Kannada, India.
SDM Centre for Research in Ayurveda and Allied Sciences, Laxminarayana Nagar, Kuthpadi, Udupi, India.
J Tradit Complement Med. 2015 Jan 13;6(1):78-88. doi: 10.1016/j.jtcme.2014.11.019. eCollection 2016 Jan.
In India, herbal medicines are mainly based on the Ayurvedic system. The main drawback of traditional medicines is a lack of standardized products. Standardization of any herbal formulation is essential in order to assess the quality, purity, safety, and efficacy of drugs based on the analysis of their active properties. Testing of Ayurvedic preparations using scientific methodologies will add to quality and authenticity of the product. This article reports standardization parameters for Hutabhugādi cūrṇa (HC) used traditionally in the treatment of Agnimāndya (digestive impairment), Pāndu (anemia), Sopha (edema), and Ārsa (piles). The formulation was prepared as per Ayurvedic Formulary of India, and it was standardized by organoleptic characterization, macro-microscopic evaluation, physicochemical testing, and thin-layer chromatography/high-performance thin-layer chromatography profiling employing a standard methodology. Results of the experiments conducted provided diagnostic characteristics to identify and standardize the formulation prepared using official ingredients of HC. Based on the data obtained, a monograph on quality standards for HC is proposed. The monograph based on the present investigation results would serve as a document to control the quality of HC.
在印度，草药主要基于阿育吠陀体系。传统药物的主要缺点是缺乏标准化产品。为了根据其活性成分的分析来评估药物的质量、纯度、安全性和疗效，对任何草药配方进行标准化都是必不可少的。使用科学方法对阿育吠陀制剂进行测试将提高产品的质量和真实性。本文报道了 Hutabhugādi cūrṇa（HC）的标准化参数，HC 传统上用于治疗 Agnimāndya（消化不良）、Pāndu（贫血）、Sopha（水肿）和 Ārsa（痔疮）。该配方是根据印度的阿育吠陀配方制备的，并通过感官特征、宏观-微观评估、物理化学测试以及使用标准方法的薄层色谱/高效薄层色谱分析进行了标准化。进行的实验结果为识别和标准化使用 HC 官方成分制备的配方提供了诊断特征。根据获得的数据，提出了 HC 质量标准专论。基于本研究结果的专论将作为控制 HC 质量的文件。
