Suppr超能文献

间歇有氧运动结合力量耐力训练对改善Zucker大鼠的代谢指标的作用超过单纯热量限制。

Interval aerobic training combined with strength-endurance exercise improves metabolic markers beyond caloric restriction in Zucker rats.

作者信息

Aparicio V A, Coll-Risco I, Camiletti-Moirón D, Nebot E, Martínez R, López-Jurado M, Aranda P

机构信息

Department of Physiology, Faculty of Pharmacy, Faculty of Sport Sciences, and Institute of Nutrition and Food Technology, University of Granada, Spain; Department of Public and Occupational Health, EMGO(+) Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands.

Department of Physiology, Faculty of Pharmacy, Faculty of Sport Sciences, and Institute of Nutrition and Food Technology, University of Granada, Spain.

出版信息

Nutr Metab Cardiovasc Dis. 2016 Aug;26(8):713-21. doi: 10.1016/j.numecd.2016.01.005. Epub 2016 Jan 18.

Abstract

AIMS

To investigate the effects of interval aerobic training combined with strength-endurance exercise (IASE) and caloric restriction (CR) on body composition, glycaemic and lipid profile and inflammatory markers.

METHODS AND RESULTS

Thirty-two Zucker diabetic fatty rats were randomised into 4 groups (sedentary + CR; sedentary + adlibitum; IASE + CR; and IASE + adlibitum). Training groups conducted an IASE programme in the same session, 5 days/week for 2 months. Body weight, fat and muscle mass and body water were measured using a body composition analyser. Plasma total, LDL and HDL cholesterol, phospholipids, triglycerides, insulin, adiponectin, tumour necrosis factor alpha, interleukin 1 and 10 were measured. Blood fasting and postprandial glucose were assessed. Body weight was lower in the CR compared to the adlibitum groups (p < 0.001). Fat mass was lower in the CR compared to the adlibitum (p < 0.05) and in the IASE compared to the sedentary groups (p < 0.001), but IASE increased lean mass (p < 0.001). Triglycerides were lower in the CR compared to the adlibitum groups (p < 0.001) whereas total and LDL-cholesterol and fasting glucose were reduced only in the IASE groups (all, p < 0.001). Phospholipids decreased in the CR compared to the adlibitum (p < 0.05) and the IASE compared to the sedentary groups (p < 0.001). The area under the curve after oral glucose tolerance test, insulin and homoeostatic model assessment were lower in the IASE and the CR compared to the sedentary and adlibitum groups, respectively (all, p < 0.001). Adiponectin was lower in the CR groups (p < 0.001).

CONCLUSION

Overall, IASE as well as CR were both useful interventions, especially when combined. However, IASE showed greater improvements on body composition, inflammatory and glycaemic profile than CR did.

摘要

目的

研究间歇性有氧运动联合力量耐力训练(IASE)及热量限制(CR)对身体成分、血糖和血脂水平以及炎症标志物的影响。

方法与结果

32只Zucker糖尿病肥胖大鼠被随机分为4组(久坐+热量限制;久坐+自由进食;IASE+热量限制;IASE+自由进食)。训练组在同一时间段进行IASE方案,每周5天,共2个月。使用身体成分分析仪测量体重、脂肪和肌肉量以及身体水分。测量血浆总胆固醇、低密度脂蛋白和高密度脂蛋白胆固醇、磷脂、甘油三酯、胰岛素、脂联素、肿瘤坏死因子α、白细胞介素1和10。评估空腹和餐后血糖。与自由进食组相比,热量限制组的体重更低(p<0.001)。与自由进食组相比,热量限制组的脂肪量更低(p<0.05),与久坐组相比,IASE组的脂肪量更低(p<0.001),但IASE增加了瘦体重(p<0.001)。与自由进食组相比,热量限制组的甘油三酯更低(p<0.001),而总胆固醇和低密度脂蛋白胆固醇以及空腹血糖仅在IASE组中降低(均为p<0.001)。与自由进食组相比,热量限制组的磷脂降低(p<0.05),与久坐组相比,IASE组的磷脂降低(p<0.001)。与久坐组和自由进食组相比,IASE组和热量限制组口服葡萄糖耐量试验后的曲线下面积、胰岛素和稳态模型评估值分别更低(均为p<0.001)。热量限制组的脂联素更低(p<0.001)。

结论

总体而言,IASE和CR都是有效的干预措施,尤其是联合使用时。然而,与CR相比,IASE在身体成分、炎症和血糖方面显示出更大的改善。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验