Department of Systems Medicine, University of Rome Tor Vergata, Roma, Italy.
School of Sports and Exercise Sciences, Telematic University San Raffaele Rome Srl, Roma, Italy.
Int J Sports Med. 2020 Oct;41(11):751-758. doi: 10.1055/a-1171-2003. Epub 2020 Jun 2.
We investigated early effects of Whole-Body Electromyostimulation added to hypocaloric diet on metabolic syndrome features in sedentary middle-aged individuals. We randomly assigned 25 patients to Whole-Body Electromyostimulation plus caloric restriction or caloric restriction alone for 26 weeks. Anthropometrics, blood pressure, fasting glucose and insulin, HOMA-IR, glycated hemoglobin, lipids, uric acid, creatinphosphokynase, C-reactive protein were assessed. Body composition was evaluated with direct-segmental, multi-frequency Bioelectrical Impedance Analysis. Both groups lost approximately 10% of weight, with similar effects on waist circumference and fat mass. Change in free-fat mass was significantly different between groups (caloric restriction -1.5±0.2 vs. Whole-Body Electromyostimulation plus caloric restriction +1.1±0.4 kg, p=0.03). Whole-Body Electromyostimulation plus caloric restriction group experienced greater percent reductions in insulin (-45.5±4.4 vs. -28.2±3.6%, p=0.002), HOMA-IR (-51.3±3.2 vs. -25.1±1.8%, p=0.001), triglycerides (-22.5±2.9 vs. -4.1±1.6%, p=0.004) and triglycerides/HDL (p=0.028). Subjects trained with Whole-Body Electromyostimulation had also significant improvement in systolic pressure (138±4 vs. 126±7 mmHg, p=0.038). No discontinuations for adverse events occurred. In middle-aged sedentary subjects with the metabolic syndrome, Whole-Body Electromyostimulation with caloric restriction for 26 weeks can improve insulin-resistance and lipid profile compared to diet alone. Further studies are needed to ascertain long-term efficacy and feasibility of this approach in individuals with the metabolic syndrome.
我们研究了全身肌肉电刺激联合低热量饮食对久坐的中年代谢综合征患者的早期影响。我们将 25 名患者随机分为全身肌肉电刺激加热量限制组或单纯热量限制组，疗程 26 周。评估人体测量学、血压、空腹血糖和胰岛素、HOMA-IR、糖化血红蛋白、血脂、尿酸、肌酸磷酸激酶、C 反应蛋白。采用直接节段多频生物电阻抗分析法评估身体成分。两组体重均减轻约 10%，腰围和脂肪量的减少效果相似。两组间游离脂肪量的变化有显著差异（热量限制组-1.5±0.2 公斤，全身肌肉电刺激加热量限制组+1.1±0.4 公斤，p=0.03）。全身肌肉电刺激加热量限制组的胰岛素（-45.5±4.4 比-28.2±3.6%，p=0.002）、HOMA-IR（-51.3±3.2 比-25.1±1.8%，p=0.001）、甘油三酯（-22.5±2.9 比-4.1±1.6%，p=0.004）和甘油三酯/高密度脂蛋白（p=0.028）的降幅更大。全身肌肉电刺激组的收缩压也有显著改善（138±4 比 126±7 毫米汞柱，p=0.038）。无因不良事件而停药的情况。在患有代谢综合征的中年久坐患者中，全身肌肉电刺激联合热量限制 26 周可改善胰岛素抵抗和血脂谱，优于单纯饮食。还需要进一步的研究来确定这种方法在代谢综合征患者中的长期疗效和可行性。
