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内镜辅助下食管末端-近端胃切除术治疗门静脉高压症食管静脉曲张——远期结果及复发机制分析

Endoscope assisted terminal esophago-proximal gastrectomy for the treatment of esophageal varices in portal hypertension--late results and an analysis of the mechanisms of recurrence.

作者信息

Takeshige K, Arakawa T, Kuroda H, Kawai Y, Yamamoto S

机构信息

First Department of Surgery, Aichi Medical University, Japan.

出版信息

Jpn J Surg. 1989 Sep;19(5):524-31. doi: 10.1007/BF02471658.

Abstract

Endoscopic assistance during terminal esophago-proximal gastrectomy (TEPG) was performed in 86 patients with portal hypertension to confirm the complete disappearance of esophageal varices and eradicate any remnants. The utility of endoscope assisted surgery (EAS), and the mechanisms of recurrent varices were thereby analyzed. Some postoperative recurrence is unavoidable after direct attack surgery as portal hypertension is often still present. Nevertheless, satisfactory disappearance was maintained in 56 cases (65 per cent) from 2 months to 9 years of follow up. Recurrent varices were observed in the other 30 cases, the causes presumably being: atrophy of the liver in 15 cases, thrombus formation in the portal vein in 10 cases, and various other causes in 5 cases; indicating increased resistance on the portal blood flow as a uniform mechanism. The episodes of rebleeding due to recurrent varices or staple ulceration in 8 cases were successfully treated by endoscopic injection sclerotherapy and medication. Actual proof of the disappearance of varices through EAS and an analysis of the mechanisms of recurrence are essential for improving the surgical techniques and treatment in cases of recurrent esophageal varices.

摘要

对86例门静脉高压患者在终末期食管近端胃切除术(TEPG)期间进行内镜辅助,以确认食管静脉曲张完全消失并根除任何残余病变。从而分析了内镜辅助手术(EAS)的效用以及静脉曲张复发的机制。由于门静脉高压通常仍然存在,直接攻击手术后一些术后复发是不可避免的。然而,在56例患者(65%)中,从2个月到9年的随访期间,静脉曲张保持了令人满意的消失状态。在其他30例患者中观察到静脉曲张复发,其原因可能是:15例肝脏萎缩,10例门静脉血栓形成,5例其他各种原因;表明门静脉血流阻力增加是一个统一的机制。8例因静脉曲张复发或吻合口溃疡引起的再出血事件通过内镜注射硬化疗法和药物治疗成功治愈。通过EAS证实静脉曲张消失以及对复发机制进行分析对于改进复发性食管静脉曲张病例的手术技术和治疗至关重要。

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