Optical Biosensors Lab, Institute of Nanoscience and Nanotechnology, NCSR "Demokritos", 15310 Athens, Greece.
Immunoassay/Immunosensors Lab, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, NCSR "Demokritos", 15310 Athens, Greece.
Biotechnol Adv. 2016 May-Jun;34(3):209-33. doi: 10.1016/j.biotechadv.2016.02.005. Epub 2016 Feb 11.
This review brings about a comprehensive presentation of the research on interferometric transducers, which have emerged as extremely promising candidates for viable, truly-marketable solutions for PoN applications due to the attested performance that has reached down to 10(-8) in term of effective refractive index changes. The review explores the operation of the various interferometric architectures along with their design, fabrication, and analytical performance aspects. The issues of biosensor functionalization and immobilization of receptors are also addressed. As a conclusion, the comparison among them is attempted in order to delve into and acknowledge their current limitations, and define the future trends.
这篇综述全面介绍了干涉传感器的研究，由于其性能已经达到有效折射率变化的 10(-8)，因此成为无源光网络应用中可行的、真正有市场潜力的解决方案的极有前途的候选者。该综述探讨了各种干涉结构的工作原理及其设计、制造和分析性能方面。还讨论了生物传感器功能化和受体固定化的问题。作为结论，尝试对它们进行了比较，以便深入了解并承认它们目前的局限性，并确定未来的趋势。
