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Structure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis.
Cell Chem Biol. 2016 Mar 17;23(3):370-380. doi: 10.1016/j.chembiol.2015.11.017. Epub 2016 Feb 11.
2
Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB.
Nature. 2015 Jan 22;517(7535):509-12. doi: 10.1038/nature13888. Epub 2014 Oct 26.
3
Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.
Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17245-17250. doi: 10.1073/pnas.1905240116. Epub 2019 Aug 13.
6
Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.
J Am Chem Soc. 2005 Nov 9;127(44):15332-3. doi: 10.1021/ja0543043.
7
Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin.
Cell Mol Life Sci. 2008 Feb;65(3):455-76. doi: 10.1007/s00018-007-7171-2.
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Brominated Variant of the Lantibiotic NAI-107 with Enhanced Antibacterial Potency.
J Nat Prod. 2015 Nov 25;78(11):2642-7. doi: 10.1021/acs.jnatprod.5b00576. Epub 2015 Oct 29.
10
Lantibiotic Reductase LtnJ Substrate Selectivity Assessed with a Collection of Nisin Derivatives as Substrates.
Appl Environ Microbiol. 2015 Jun;81(11):3679-87. doi: 10.1128/AEM.00475-15. Epub 2015 Mar 20.

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Promiscuity of lanthipeptide enzymes: new challenges and applications.
World J Microbiol Biotechnol. 2025 Aug 6;41(8):298. doi: 10.1007/s11274-025-04505-5.
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Structural insights into the substrate binding mechanism of the class I dehydratase MadB.
Commun Biol. 2025 Jul 9;8(1):1032. doi: 10.1038/s42003-025-08454-5.
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Enabling Access to Novel Bacterial Biosynthetic Potential From ONT Draft Genomic Data.
Microb Biotechnol. 2025 Mar;18(3):e70104. doi: 10.1111/1751-7915.70104.
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Embleporicin: A Novel Class I Lanthipeptide from the Actinobacteria sp. NF3.
Antibiotics (Basel). 2024 Dec 5;13(12):1179. doi: 10.3390/antibiotics13121179.
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Activity of Gut-Derived Nisin-like Lantibiotics against Human Gut Pathogens and Commensals.
ACS Chem Biol. 2024 Feb 16;19(2):357-369. doi: 10.1021/acschembio.3c00577. Epub 2024 Jan 31.
7
Improved production of class I lanthipeptides in .
Chem Sci. 2023 Feb 13;14(10):2537-2546. doi: 10.1039/d2sc06597e. eCollection 2023 Mar 8.
8
-Elimination of glutamylated threonine in lanthipeptide biosynthesis.
Chem Commun (Camb). 2023 Jan 26;59(9):1165-1168. doi: 10.1039/d2cc06345j.
9
A scalable platform to discover antimicrobials of ribosomal origin.
Nat Commun. 2022 Oct 17;13(1):6135. doi: 10.1038/s41467-022-33890-w.
10
Class V Lanthipeptide Cyclase Directs the Biosynthesis of a Stapled Peptide Natural Product.
J Am Chem Soc. 2022 Sep 28;144(38):17549-17557. doi: 10.1021/jacs.2c06808. Epub 2022 Sep 15.

本文引用的文献

1
The enterococcal cytolysin synthetase has an unanticipated lipid kinase fold.
Elife. 2015 Jul 30;4:e07607. doi: 10.7554/eLife.07607.
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A prevalent peptide-binding domain guides ribosomal natural product biosynthesis.
Nat Chem Biol. 2015 Aug;11(8):564-70. doi: 10.1038/nchembio.1856. Epub 2015 Jul 13.
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Structural analysis of leader peptide binding enables leader-free cyanobactin processing.
Nat Chem Biol. 2015 Aug;11(8):558-563. doi: 10.1038/nchembio.1841. Epub 2015 Jun 22.
4
The PqqD homologous domain of the radical SAM enzyme ThnB is required for thioether bond formation during thurincin H maturation.
FEBS Lett. 2015 Jul 8;589(15):1802-6. doi: 10.1016/j.febslet.2015.05.032. Epub 2015 May 27.
5
Expanded natural product diversity revealed by analysis of lanthipeptide-like gene clusters in actinobacteria.
Appl Environ Microbiol. 2015 Jul;81(13):4339-50. doi: 10.1128/AEM.00635-15. Epub 2015 Apr 17.
6
Engineering the heterologous expression of lanthipeptides in Escherichia coli by multigene assembly.
Appl Microbiol Biotechnol. 2015 Aug;99(15):6351-61. doi: 10.1007/s00253-015-6557-6. Epub 2015 Apr 7.
8
Family of class I lantibiotics from actinomycetes and improvement of their antibacterial activities.
ACS Chem Biol. 2015 Apr 17;10(4):1034-42. doi: 10.1021/cb500878h. Epub 2015 Jan 23.
10
Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB.
Nature. 2015 Jan 22;517(7535):509-12. doi: 10.1038/nature13888. Epub 2014 Oct 26.

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