膝曲大戟中的三种新三萜类化合物：膝曲大戟内酯A、B和C

Genicunolide A, B and C: three new triterpenoids from Euphorbia geniculata.

作者信息

Farozi Alia, Banday Javid Ahmad, Shah Shakeel Ahmad

机构信息

Department of Chemistry, National Institute of Technology, Hazratbal, Srinagar-190006, J&K, India, Tel.: +91 9906626635.

出版信息

Beilstein J Org Chem. 2015 Dec 23;11:2707-12. doi: 10.3762/bjoc.11.291. eCollection 2015.

DOI:10.3762/bjoc.11.291

PMID:26877792

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4734298/

Abstract

Three new triterpenoids, designated as genicunolide A (1), B (2) and C (3), along with friedelin (4) and friedelinol (5), were isolated from the aerial parts of Euphorbia geniculata. They were characterized as 1β-acetoxy-3β-hydroxy-11α,12α-oxidotaraxer-14-ene, 1β,3β-diacetoxy-21α-hydroxy-11α,12α-oxidotaraxer-14-ene and 3β,9α,20α-trihydroxy-Ψ-taraxast-5-ene, respectively, by spectral and chemical methods.

摘要

从泽漆地上部分分离得到3个新的三萜类化合物，分别命名为膝状大戟内酯A（1）、B（2）和C（3），以及木栓酮（4）和木栓醇（5）。通过光谱和化学方法，它们分别被鉴定为1β-乙酰氧基-3β-羟基-11α,12α-环氧蒲公英赛-14-烯、1β,3β-二乙酰氧基-21α-羟基-11α,12α-环氧蒲公英赛-14-烯和3β,9α,20α-三羟基-Ψ-蒲公英甾-5-烯。