Cachet Xavier, Langrand Jerome, Bottai Cecile, Dufat Hanh, Locatelli-Jouans Corinne, Nossin Emmanuel, Boucaud-Maitre Denis
Laboratoire de Pharmacognosie, UMR 8638 COMETE CNRS, Faculté de Pharmacie, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Centre Antipoison de Paris, AP-HP Hôpital Lariboisière, Paris, France.
Toxicon. 2016 May;114:28-30. doi: 10.1016/j.toxicon.2016.02.013. Epub 2016 Feb 12.
"Chiniy-trèf" is a traditional medicinal preparation used in Martinique, French West Indies, for the prevention of all kinds of attempted poisoning and hex. It is produced by the maceration in alcohol (mostly rum) of larvae (caterpillars) of the butterfly Battus polydamas ssp. cebriones, feeding on the leaves of Aristolochia trilobata. Aristolochic acids I and II that are well-known nephrotoxic and carcinogenic substances were identified on two samples of "chiniy-trèfl" by chromatographic methods.
“Chiniy-trèf”是法属西印度群岛马提尼克岛用于预防各类中毒企图和诅咒的一种传统药物制剂。它由以三叶马兜铃叶为食的多音凤蝶(Battus polydamas ssp. cebriones)幼虫(毛虫)在酒精(主要是朗姆酒)中浸渍制成。通过色谱法在两份“chiniy-trèfl”样品中鉴定出了已知具有肾毒性和致癌性的马兜铃酸I和II。